Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 7/20 | 0.87 |
| ▸ | HTR2C | P28335 | 4/20 | 0.87 |
| ▸ | HTR7 | P34969 | 4/20 | 0.87 |
| ▸ | HTR6 | P50406 | 4/20 | 0.87 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.84 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.84 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.84 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7418228 | 0.99 | HTR2A (0.85) | HTR2AHTR2CHTR7HTR6KDM4E | |
| SCHEMBL4211202 | 0.91 | HTR2A (1.00) | HTR2AHTR2CHTR7HTR6KDM4E | |
| SCHEMBL7839803 | 0.90 | HTR2A (1.00) | HTR2AHTR2CHTR7HTR6KDM4E | |
| Hydrochloric Acid SCHEMBL9375390 | 0.90 | HTR2A (0.98) | HTR2AHTR2CHTR7HTR6KDM4E | |
| SCHEMBL9373922 | 0.90 | HTR2A (0.98) | HTR2AHTR2CHTR7HTR6KDM4E | |
| Hydrochloric Acid SCHEMBL9374754 | 0.89 | HTR2A (0.95) | HTR2AHTR2CHTR7HTR6KDM4E | |
| Oxalic Acid SCHEMBL467239 | 0.89 | HTR2A (0.95) | HTR2AHTR2CHTR7HTR6KDM4E | |
| Hydrochloric Acid SCHEMBL7828801 | 0.89 | HTR2A (0.97) | HTR2AHTR2CHTR7HTR6KDM4E | |
| SCHEMBL1583307 | 0.87 | HTR2A (0.88) | HTR2AHTR2CHTR7HTR6KDM4E | |
| SCHEMBL9172271 | 0.87 | HTR2A (0.82) | HTR2AHTR2CHTR7HTR6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546100-B1 | NEW BENZOYL PIPERIDINE COMPOUNDS | SK HOLDINGS CO LTD (KR) | 2011-04-20 | — | — | EP | claimed |
| EP-0229391-B1 | PIPERIDINE DERIVATE, ITS USE AND PHARMACEUTICAL COMPOSITION CONTAINING IT | Eisai Co., Ltd. (JP) | 1992-07-29 | — | — | EP | claimed |
| WO-2004018423-A1 | NEW BENZOYL PIPERIDINE COMPOUNDS | SK CORPORATION (KR) | 2004-03-04 | — | — | WO | disclosed |
| EP-0360275-B1 | Imidazole antiarrhythmics | MERRELL DOW PHARMA (US) | 1994-01-12 | — | — | EP | disclosed |
| US-5198449-A | N-substituted alpha-arylazacycloalkylmethanamines and their use as cardiovascular agents | A. H. ROBINS COMPANY INCORPORATED (US) | 1993-03-30 | — | — | US | disclosed |
| EP-0360275-A2 | Imidazole antiarrhythmics | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-03-28 | — | — | EP | disclosed |
| US-4868194-A | Imidazole antiarrhythmics | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-09-19 | — | — | US | disclosed |