⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7291798 | 0.92 | HRH4 (0.37) | — | |
| SCHEMBL9572593 | 0.89 | HRH4 (0.39) | — | |
| SCHEMBL672563 | 0.81 | — | — | |
| SCHEMBL5839106 | 0.81 | HRH4 (0.39) | — | |
| SCHEMBL7834390 | 0.81 | HRH4 (0.43) | — | |
| SCHEMBL14176497 | 0.78 | HRH4 (0.45) | — | |
| SCHEMBL13884273 | 0.78 | HRH4 (0.45) | — | |
| SCHEMBL13884287 | 0.78 | HRH4 (0.45) | — | |
| SCHEMBL13884243 | 0.78 | HRH4 (0.45) | — | |
| SCHEMBL18351665 | 0.78 | HRH4 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1647555-B1 | THE C-GLYCOSYLISOFLAVONES HAVING ALKYLAMINOALKOXYL SUBSTITUENT, THE PREPARATION AND THE USE OF THE SAME | INST RADIATION MED AMMS PLA (CN) | 2011-04-20 | — | — | EP | claimed |
| US-7727965-B2 | C-glycosylisoflavones having alkylaminoalkoxyl substituent, preparation and use of the same | HAINAN YANGPU NEW & SPECIAL MEDICINE CO., LTD. (CN) | 2010-06-01 | — | — | US | claimed |
| US-20080293642-A1 | C-Glycosylisoflavones Having Alkylaminoalkoxyl Substituent, Preparation and Use of the Same | INSTITUTE OF RADIATION MEDICINE, ACADEMY OF MILITARY MEDICAL SCIENCES, PLA (CN) | 2008-11-27 | — | — | US | claimed |
| EP-1647555-A1 | THE C-GLYCOSYLISOFLAVONES HAVING ALKYLAMINOALKOXYL SUBSTITUENT, THE PREPARATION AND THE USE OF THE SAME | Institute of Radiation Medicine Academy of Military Medical Sciences of the Pla (CN) | 2006-04-19 | — | — | EP | claimed |
| EP-1076649-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 2001-02-21 | — | — | EP | claimed |
| US-6127381-A | A MELANOCORTIN RECEPTOR LIGAND FOR REGULATING FOOD INTAKE AND BODY WEIGHT, REGULATING CYTOKINE ACTIVITY, ANTI-INFLAMMATORY ACTIVITY | LION BIOSCIENCE AG (DE) | 2000-10-03 | — | — | US | claimed |
| WO-1999055679-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 1999-11-04 | — | — | WO | claimed |
| EP-1647555-B1 | THE C-GLYCOSYLISOFLAVONES HAVING ALKYLAMINOALKOXYL SUBSTITUENT, THE PREPARATION AND THE USE OF THE SAME | INST RADIATION MED AMMS PLA (CN) | 2011-04-20 | — | — | EP | disclosed |
| US-7727965-B2 | C-glycosylisoflavones having alkylaminoalkoxyl substituent, preparation and use of the same | HAINAN YANGPU NEW & SPECIAL MEDICINE CO., LTD. (CN) | 2010-06-01 | — | — | US | disclosed |
| US-20080293642-A1 | C-Glycosylisoflavones Having Alkylaminoalkoxyl Substituent, Preparation and Use of the Same | INSTITUTE OF RADIATION MEDICINE, ACADEMY OF MILITARY MEDICAL SCIENCES, PLA (CN) | 2008-11-27 | — | — | US | disclosed |
| EP-1647555-A1 | THE C-GLYCOSYLISOFLAVONES HAVING ALKYLAMINOALKOXYL SUBSTITUENT, THE PREPARATION AND THE USE OF THE SAME | Institute of Radiation Medicine Academy of Military Medical Sciences of the Pla (CN) | 2006-04-19 | — | — | EP | disclosed |
| US-6608082-B1 | Treatment of erectile dysfunction using isoquinoline compound melanocortin receptor ligands | LION BIOSCIENCE AG (DE) | 2003-08-19 | — | — | US | disclosed |
| EP-1076649-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 2001-02-21 | — | — | EP | disclosed |
| US-5434164-A | Carbostyril derivatives and salts thereof and pharmaceutical compositions for inhibiting adhesion of thrombocytes | OTSUKA PHARMACEUTICAL CO. LTD. (JP) | 1995-07-18 | — | — | US | disclosed |
| EP-0240015-B1 | Carbostyril derivatives, process for preparing them, pharmaceutical composition, and use | OTSUKA PHARMA CO LTD (JP) | 1994-12-28 | — | — | EP | disclosed |
| EP-0562832-A1 | Indole and indazole derivatives, for the treatment and prophylaxis of cerebral disorders, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-5008274-A | Carbostyril derivatives and salts thereof and pharmaceutical composition for inhibiting adhesion of thrombocytes | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-04-16 | — | — | US | disclosed |
| US-4990406-A | Blends of a vinylidene fluoride, tetrafluoroethylene, chlorotrifluoroethylene terpolymer; linings | SOCIETE ATOCHEM (FR) | 1991-02-05 | — | — | US | disclosed |
| EP-0240015-A2 | Carbostyril derivatives, process for preparing them, pharmaceutical composition, and use | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-10-07 | — | — | EP | disclosed |
| US-4206117-A | Pyridinyl aminoalkyl ethers | BASF AKTIENGESELLSCHAFT (DE) | 1980-06-03 | — | — | US | disclosed |