⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1582610 | 0.81 | — | — | |
| SCHEMBL7291798 | 0.79 | HRH4 (0.37) | — | |
| SCHEMBL238451 | 0.78 | KDM4E (0.34) | — | |
| SCHEMBL9572593 | 0.77 | HRH4 (0.39) | — | |
| SCHEMBL9243587 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL13859413 | 0.74 | KDM4E (0.38) | — | |
| SCHEMBL5495057 | 0.74 | KDM4E (0.33) | — | |
| SCHEMBL5839106 | 0.72 | HRH4 (0.39) | — | |
| SCHEMBL28434 | 0.72 | — | — | |
| SCHEMBL7834390 | 0.72 | HRH4 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 283 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114502362-A | Contact lenses with surfaces of varying softness | 爱尔康公司 | 2022-05-13 | — | — | CN | claimed |
| EP-3862354-A1 | INDOLOPYRIDINES AS EG5 KINESIN MODULATORS | 4SC AG (DE) | 2021-08-11 | — | — | EP | claimed |
| EP-2824105-B1 | Indolopyridines as Eg5 kinesin modulators | 4SC AG (DE) | 2021-03-31 | — | — | EP | claimed |
| CN-106083855-B | Purine derivatives useful as Hsp90 inhibitors | 斯隆-凯特林癌症研究院 | 2020-04-10 | — | — | CN | claimed |
| EP-3091019-B1 | PURINE DERIVATIVES USEFUL AS HSP90 INHIBITORS | SLOAN KETTERING INST CANCER RES (US) | 2019-04-03 | — | — | EP | claimed |
| US-10172863-B2 | Purine derivatives useful as HSP90 inhibitors | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2019-01-08 | — | — | US | claimed |
| US-20160310497-A1 | PURINE DERIVATIVES USEFUL AS HSP90 INHIBITORS | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH | 2016-10-27 | — | — | US | claimed |
| EP-2486039-B1 | PURINE DERIVATIVES USEFUL AS HSP90 INHIBITORS | SLOAN KETTERING INST CANCER (US) | 2016-06-01 | — | — | EP | claimed |
| US-9328114-B2 | Hsp90 inhibitors | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2016-05-03 | — | — | US | claimed |
| EP-2824105-A1 | Indolopyridines as Eg5 kinesin modulators | 4SC AG (DE) | 2015-01-14 | — | — | EP | claimed |
| EP-1647555-B1 | THE C-GLYCOSYLISOFLAVONES HAVING ALKYLAMINOALKOXYL SUBSTITUENT, THE PREPARATION AND THE USE OF THE SAME | INST RADIATION MED AMMS PLA (CN) | 2011-04-20 | — | — | EP | claimed |
| US-20110027226-A1 | INDOLOPYRIDINES AS INHIBITORS OF THE KINESIN SPINDLE PROTEIN (EG5) | 4SC AG (DE) | 2011-02-03 | — | — | US | claimed |
| US-7834181-B2 | Small-molecule Hsp90 inhibitors | SLAON-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2010-11-16 | — | — | US | claimed |
| US-7727965-B2 | C-glycosylisoflavones having alkylaminoalkoxyl substituent, preparation and use of the same | HAINAN YANGPU NEW & SPECIAL MEDICINE CO., LTD. (CN) | 2010-06-01 | — | — | US | claimed |
| US-20090246169-A1 | INDOLOPYRIDINES AS EG5 KINESIN MODULATORS | NYCOMED GMBH (DE) | 2009-10-01 | — | — | US | claimed |
| US-20090233902-A1 | INDOLOPYRIDINES AS EG5 KINESIN MODULATORS | 4SC AG (DE) | 2009-09-17 | — | — | US | claimed |
| EP-2033962-A1 | Tetracyclic indolopyridines as EG5 inhibitors | 4SC AG (DE) | 2009-03-11 | — | — | EP | claimed |
| US-20080293642-A1 | C-Glycosylisoflavones Having Alkylaminoalkoxyl Substituent, Preparation and Use of the Same | INSTITUTE OF RADIATION MEDICINE, ACADEMY OF MILITARY MEDICAL SCIENCES, PLA (CN) | 2008-11-27 | — | — | US | claimed |
| EP-1647555-A1 | THE C-GLYCOSYLISOFLAVONES HAVING ALKYLAMINOALKOXYL SUBSTITUENT, THE PREPARATION AND THE USE OF THE SAME | Institute of Radiation Medicine Academy of Military Medical Sciences of the Pla (CN) | 2006-04-19 | — | — | EP | claimed |
| US-5091492-A | Copolymer of polcyclic compound contiaing (meth)acryloyloxy group and unsaturated monomer | NIPPON OIL AND FATS CO., LTD. (JP) | 1992-02-25 | — | — | US | claimed |