Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 9/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15827073 | 0.89 | KDR (0.54) | KDRMAPTL3MBTL1SMN1; SMN2TDP1 | |
| SCHEMBL11616761 | 0.89 | KDR (0.53) | KDRMAPTL3MBTL1SMN1; SMN2TDP1 | |
| SCHEMBL15827084 | 0.87 | KDR (0.60) | KDRMAPTL3MBTL1SMN1; SMN2TDP1 | |
| SCHEMBL3381131 | 0.85 | KDR (0.48) | KDRMAPTL3MBTL1SMN1; SMN2TDP1 | |
| SCHEMBL3381126 | 0.85 | KDR (0.48) | KDRMAPTL3MBTL1SMN1; SMN2TDP1 | |
| SCHEMBL2769578 | 0.83 | KDR (0.46) | KDRMAPTL3MBTL1SMN1; SMN2TDP1 | |
| SCHEMBL2769580 | 0.83 | KDR (0.46) | KDRMAPTL3MBTL1SMN1; SMN2TDP1 | |
| SCHEMBL15826861 | 0.82 | MAPT (0.40) | KDRMAPTL3MBTL1SMN1; SMN2TDP1 | |
| Bromide SCHEMBL2769938 | 0.82 | KDR (0.46) | KDRMAPTL3MBTL1SMN1; SMN2TDP1 | |
| Bromide SCHEMBL2769935 | 0.82 | KDR (0.46) | KDRMAPTL3MBTL1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8759508-B2 | Chromophoric silyl protecting groups and their use in the chemical synthesis of oligonucleotides | GE HEALTHCARE DHARMACON, INC. (US) | 2014-06-24 | — | — | US | disclosed |