Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 7/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.36 |
| ▸ | MEN1 | O00255 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3381126 | 1.00 | KDR (0.48) | KDRMAPTL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL15827073 | 0.89 | KDR (0.54) | KDRMAPTL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL11616761 | 0.89 | KDR (0.53) | KDRMAPTL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL15827084 | 0.87 | KDR (0.60) | KDRMAPTL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL15826858 | 0.85 | KDR (0.48) | KDRMAPTL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL2769578 | 0.83 | KDR (0.46) | KDRMAPTL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL2769580 | 0.83 | KDR (0.46) | KDRMAPTL3MBTL1SMN1; SMN2NPC1 | |
| Bromide SCHEMBL2769938 | 0.82 | KDR (0.46) | KDRMAPTL3MBTL1SMN1; SMN2NPC1 | |
| Bromide SCHEMBL2769935 | 0.82 | KDR (0.46) | KDRMAPTL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL810844 | 0.81 | KDR (0.44) | KDRMAPTL3MBTL1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433473-B1 | Dyeing composition containing a specific polycationic direct dye, method of dyeing, use and multicompartment device | OREAL (FR) | 2010-11-17 | — | — | EP | claimed |
| US-7241319-B2 | Dye composition comprising at least one polycationic direct dye, dyeing processes, uses, and multi-compartment devices | L'OREAL S.A. (FR) | 2007-07-10 | — | — | US | claimed |
| US-20040194229-A1 | Dye composition comprising at least one polycationic direct dye, dyeing processes, uses, and multi-compartment devices | L'OREAL S.A. (FR) | 2004-10-07 | — | — | US | claimed |
| US-7241319-B2 | Dye composition comprising at least one polycationic direct dye, dyeing processes, uses, and multi-compartment devices | L'OREAL S.A. (FR) | 2007-07-10 | — | — | US | disclosed |
| US-20040194229-A1 | Dye composition comprising at least one polycationic direct dye, dyeing processes, uses, and multi-compartment devices | L'OREAL S.A. (FR) | 2004-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040194229-A1 | Dye composition comprising at least one polycationic direct dye, dyeing processes, uses, and multi-compartment devices | COL14A1, COL1A1, KRT18 | KDR 4534/4885MAPT 477/4885L3MBTL1 4242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.