Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | XDH | P47989 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL111187 | 0.88 | CA12 (0.58) | ATAD2CA12CA1CA2CA7 | |
| SCHEMBL19477839 | 0.88 | FURIN (0.38) | ATAD2KDM4EGAAMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL111186 | 0.86 | CA12 (0.56) | ATAD2CA12CA1CA2CA7 | |
| SCHEMBL654773 | 0.84 | CA1 (0.58) | ATAD2CA12CA1CA2CA7 | |
| SCHEMBL14190699 | 0.83 | CA12 (0.70) | CA12CA1CA2CA7CA9 | |
| SCHEMBL30938200 | 0.82 | ATAD2 (0.47) | ATAD2CA12CA1CA2CA7 | |
| SCHEMBL29259919 | 0.82 | ATAD2 (0.47) | ATAD2CA12CA1CA2CA7 | |
| Hydrochloric Acid SCHEMBL9494959 | 0.82 | CA1 (0.56) | ATAD2CA12CA1CA2CA7 | |
| SCHEMBL10600019 | 0.81 | CA12 (0.50) | ATAD2CA12CA1CA2CA7 | |
| SCHEMBL4731090 | 0.81 | CA12 (0.50) | ATAD2CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2277854-B1 | Synthesis of iodixanol in 1-methoxy-2-propanol and water or methanol | GE HEALTHCARE AS (NO) | 2014-06-25 | — | — | EP | disclosed |