Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.57 |
| ▸ | DRD4 | P21917 | 2/20 | 0.57 |
| ▸ | DRD3 | P35462 | 2/20 | 0.57 |
| ▸ | HTR1A | P08908 | 7/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.50 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1583031 | 0.99 | DRD2 (0.56) | DRD2DRD4DRD3HTR1ASLC6A4 | |
| SCHEMBL1582402 | 0.93 | DRD2 (0.57) | DRD2DRD4DRD3HTR1ASLC6A4 | |
| Hydrochloric Acid SCHEMBL1582976 | 0.92 | DRD2 (0.56) | DRD2DRD4DRD3HTR1ASLC6A4 | |
| SCHEMBL1582678 | 0.92 | DRD2 (0.61) | DRD2DRD4DRD3HTR1ASLC6A4 | |
| Hydrochloric Acid SCHEMBL1582324 | 0.91 | DRD2 (0.60) | DRD2DRD4DRD3HTR1ASLC6A4 | |
| SCHEMBL1582888 | 0.89 | DRD2 (0.59) | DRD2DRD4DRD3HTR1ASLC6A4 | |
| SCHEMBL1582251 | 0.89 | DRD2 (0.61) | DRD2DRD4DRD3HTR1ASLC6A4 | |
| Hydrochloric Acid SCHEMBL1582510 | 0.88 | DRD2 (0.58) | DRD2DRD4DRD3HTR1ASLC6A4 | |
| SCHEMBL1583046 | 0.88 | DRD2 (0.58) | DRD2DRD4DRD3HTR1ASLC6A4 | |
| Hydrochloric Acid SCHEMBL1582642 | 0.88 | DRD2 (0.60) | DRD2DRD4DRD3HTR1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1292592-B1 | HETEROCYCLIC AMINOALKYL PYRIDINE DERIVATIVES AS PSYCHOPHARMACEUTICALS | MERCK PATENT GMBH (DE) | 2011-04-20 | — | — | EP | claimed |
| EP-1292592-B1 | HETEROCYCLIC AMINOALKYL PYRIDINE DERIVATIVES AS PSYCHOPHARMACEUTICALS | MERCK PATENT GMBH (DE) | 2011-04-20 | — | — | EP | disclosed |