Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | BDKRB2 | P30411 | 2/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1582889 | 0.99 | MEN1 (0.51) | MEN1KMT2ABDKRB2MCHR1HTR1A | |
| Hydrochloric Acid SCHEMBL1582547 | 0.99 | MEN1 (0.51) | MEN1KMT2ABDKRB2MCHR1HTR1A | |
| SCHEMBL1583476 | 0.92 | MEN1 (0.47) | MEN1KMT2ABDKRB2MCHR1HTR1A | |
| Hydrochloric Acid SCHEMBL1583121 | 0.92 | MEN1 (0.47) | MEN1KMT2ABDKRB2MCHR1HTR1A | |
| SCHEMBL1582788 | 0.89 | MEN1 (0.46) | MEN1KMT2ABDKRB2MCHR1HTR1A | |
| Hydrochloric Acid SCHEMBL1582817 | 0.88 | MEN1 (0.45) | MEN1KMT2ABDKRB2MCHR1HTR1A | |
| SCHEMBL1583365 | 0.87 | GLRA3 (0.51) | MEN1KMT2AMCHR1HTR1AKDM4E | |
| Hydrochloric Acid SCHEMBL1582269 | 0.86 | GLRA3 (0.50) | MEN1KMT2AMCHR1HTR1AKDM4E | |
| Hydrochloric Acid SCHEMBL1582253 | 0.86 | GLRA3 (0.50) | MEN1KMT2AMCHR1HTR1AKDM4E | |
| SCHEMBL7394277 | 0.83 | HTR1B (0.49) | KMT2AHTR1AKDM4EDRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1292592-B1 | HETEROCYCLIC AMINOALKYL PYRIDINE DERIVATIVES AS PSYCHOPHARMACEUTICALS | MERCK PATENT GMBH (DE) | 2011-04-20 | — | — | EP | claimed |
| EP-1292592-B1 | HETEROCYCLIC AMINOALKYL PYRIDINE DERIVATIVES AS PSYCHOPHARMACEUTICALS | MERCK PATENT GMBH (DE) | 2011-04-20 | — | — | EP | disclosed |