Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA3 | O75311 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GLRB | P48167 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NMT2 | O60551 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1582253 | 0.99 | GLRA3 (0.50) | GLRA3RAB9AMEN1NPC1KMT2A | |
| Hydrochloric Acid SCHEMBL1582269 | 0.99 | GLRA3 (0.50) | GLRA3RAB9AMEN1NPC1KMT2A | |
| SCHEMBL1583360 | 0.92 | GLRA3 (0.47) | GLRA3RAB9AMEN1NPC1KMT2A | |
| Hydrochloric Acid SCHEMBL1582650 | 0.91 | GLRA3 (0.46) | GLRA3RAB9AMEN1NPC1KMT2A | |
| SCHEMBL1583519 | 0.88 | GLRA3 (0.45) | GLRA3RAB9AMEN1NPC1KMT2A | |
| Hydrochloric Acid SCHEMBL1582764 | 0.87 | GLRA3 (0.45) | GLRA3RAB9AMEN1NPC1KMT2A | |
| SCHEMBL1582986 | 0.87 | MEN1 (0.52) | MEN1KMT2AKDM4ELMNAMCHR1 | |
| Hydrochloric Acid SCHEMBL1582547 | 0.86 | MEN1 (0.51) | MEN1KMT2AKDM4ELMNAMCHR1 | |
| Hydrochloric Acid SCHEMBL1582889 | 0.86 | MEN1 (0.51) | MEN1KMT2AKDM4ELMNAMCHR1 | |
| SCHEMBL1583056 | 0.85 | KDM4E (0.45) | KMT2AMAPTKDM4ECYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1292592-B1 | HETEROCYCLIC AMINOALKYL PYRIDINE DERIVATIVES AS PSYCHOPHARMACEUTICALS | MERCK PATENT GMBH (DE) | 2011-04-20 | — | — | EP | claimed |
| EP-1292592-B1 | HETEROCYCLIC AMINOALKYL PYRIDINE DERIVATIVES AS PSYCHOPHARMACEUTICALS | MERCK PATENT GMBH (DE) | 2011-04-20 | — | — | EP | disclosed |