Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INMT | O95050 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3085654 | 0.67 | — | — | |
| SCHEMBL19059893 | 0.65 | MAPT (0.47) | — | |
| SCHEMBL14368169 | 0.63 | — | — | |
| SCHEMBL15833505 | 0.63 | — | — | |
| SCHEMBL24664061 | 0.61 | ALDH1A1 (0.45) | INMT | |
| SCHEMBL13955322 | 0.61 | MAOB (0.31) | INMT | |
| SCHEMBL16339701 | 0.60 | KDM4E (0.44) | — | |
| SCHEMBL16339700 | 0.60 | KDM4E (0.44) | — | |
| SCHEMBL570057 | 0.58 | — | — | |
| SCHEMBL13453304 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014100695-A1 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-06-26 | — | — | WO | disclosed |