SCHEMBL15834779

SCHEMBL15834779

Cc1ccc(Oc2ccc(-c3nc4ccc(-c5ccc6nc(C)[nH]c6c5)cc4[nH]3)cc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHEK2 O96017 7/20 0.65
NPC1 O15118 4/20 0.60
RAB9A P51151 4/20 0.60
MEN1 O00255 3/20 0.60
KMT2A Q03164 3/20 0.60
POLB P06746 2/20 0.60
SMN1; SMN2 Q16637 2/20 0.60
HPSE Q9Y251 1/20 0.60
ALDH1A1 P00352 2/20 0.59
MAPT P10636 2/20 0.59
KDM4E B2RXH2 1/20 0.59
GLA P06280 1/20 0.59
GAA P10253 1/20 0.59
GFER P55789 1/20 0.59
RXFP1 Q9HBX9 1/20 0.59
NPBWR1 P48145 2/20 0.55
NFKB1 P19838 1/20 0.55
MAPK1 P28482 1/20 0.55
HTT P42858 1/20 0.55
NFKB2 Q00653 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26357465 0.95 CHEK2 (0.60) CHEK2NPC1RAB9AMEN1KMT2A
SCHEMBL18794741 0.95 CHEK2 (0.65) CHEK2NPC1RAB9AMEN1KMT2A
SCHEMBL22383437 0.92 CHEK2 (0.60) CHEK2NPC1RAB9AMEN1KMT2A
SCHEMBL34880 0.92 MEN1 (0.70) CHEK2NPC1RAB9AMEN1KMT2A
SCHEMBL26042614 0.90 CHEK2 (0.60) CHEK2NPC1RAB9AMEN1KMT2A
SCHEMBL9986883 0.89 CHEK2 (0.55) CHEK2NPC1RAB9AMEN1KMT2A
SCHEMBL26357451 0.88 CHEK2 (0.58) CHEK2NPC1RAB9AMEN1KMT2A
SCHEMBL13120680 0.87 NPC1 (0.68) CHEK2NPC1RAB9AMEN1KMT2A
SCHEMBL13041694 0.86 MEN1 (0.68) CHEK2NPC1RAB9AMEN1KMT2A
SCHEMBL34856 0.86 MEN1 (0.68) CHEK2NPC1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10294129-B2 Polymeric-metal composite electrode-based electrochemical device for generating oxidants GENERAL ELECTRIC COMPANY (US) 2019-05-21 US disclosed
EP-2935125-B1 ELECTROCHEMICAL WATER TREATMENT SYSTEM AND METHOD GEN ELECTRIC (US) 2017-08-02 EP disclosed
US-20170073251-A1 POLYMERIC-METAL COMPOSITE ELECTRODE-BASED ELECTROCHEMICAL DEVICE FOR GENERATING OXIDANTS GENERAL ELECTRIC COMPANY (US) 2017-03-16 US disclosed
US-20150344333-A1 ELECTROCHEMICAL WATER TREATMENT SYSTEM AND METHOD BL TECHNOLOGIES, INC. 2015-12-03 US disclosed
WO-2014099434-A1 ELECTROCHEMICAL WATER TREATMENT SYSTEM AND METHOD GENERAL ELECTRIC COMPANY (US) 2014-06-26 WO disclosed