SCHEMBL34880

SCHEMBL34880

Cc1ccc(-c2nc3ccc(-c4ccc5nc(C)[nH]c5c4)cc3[nH]2)cc1

nearest known ligand 0.87

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.70
KMT2A Q03164 6/20 0.70
NPC1 O15118 5/20 0.70
RAB9A P51151 5/20 0.70
SMN1; SMN2 Q16637 4/20 0.70
POLB P06746 3/20 0.70
ALDH1A1 P00352 4/20 0.68
MAPT P10636 4/20 0.68
RXFP1 Q9HBX9 3/20 0.68
KDM4E B2RXH2 3/20 0.68
GLA P06280 3/20 0.68
GAA P10253 2/20 0.68
GFER P55789 2/20 0.68
NPBWR1 P48145 2/20 0.63
NFKB1 P19838 2/20 0.63
MAPK1 P28482 2/20 0.63
HTT P42858 1/20 0.63
NFKB2 Q00653 1/20 0.63
RELA Q04206 1/20 0.63
CHEK2 O96017 3/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13120680 0.95 NPC1 (0.68) MEN1KMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL34856 0.94 MEN1 (0.68) MEN1KMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL13041694 0.94 MEN1 (0.68) MEN1KMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL13287104 0.94 MEN1 (0.68) MEN1KMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL12304983 0.93 NPBWR1 (0.69) MEN1KMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL15834779 0.92 CHEK2 (0.65) MEN1KMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL14665476 0.90 NPC1 (0.75) MEN1KMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL34960 0.90 NPC1 (0.60) MEN1KMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL15747134 0.90 RAB9A (0.59) MEN1KMT2ANPC1RAB9ASMN1; SMN2
SCHEMBL30572488 0.90 RAB9A (0.59) MEN1KMT2ANPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170165614-A1 ASYMMETRIC MEMBRANES FOR USE IN NANOFILTRATION IP2IPO INNOVATIONS LIMITED (GB) 2017-06-15 US disclosed
US-9680156-B2 Composition, polymer thereof, electrode and electrolyte membrane for fuel cell, and fuel cell including the same SAMSUNG ELECTRONICS CO., LTD (KR) 2017-06-13 US disclosed
US-9515341-B2 Porous membrane, electrolyte membrane including same, methods of manufacturing both, and fuel cell including at least one of the membranes SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-12-06 US disclosed
US-9484588-B2 Compound, composition including compound, composite formed therefrom, electrode using composition or composite, composite membrane using composite, and fuel cell including at least one selected from electrode and composite membrane SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-11-01 US disclosed
US-20160268609-A1 COMPOSITION, METHOD OF PREPARING THE COMPOSITION, ELECTRODE INCLUDING THE COMPOSITION, AND FUEL CELL INCLUDING THE ELECTRODE SAMSUNG ELECTRONICS CO LTD (KR) 2016-09-15 US disclosed
US-9368803-B2 Composition, method of preparing the composition, electrode including the composition, and fuel cell including the electrode SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-14 US disclosed
US-9178237-B2 Conductive composition and method of preparation, polymer thereof, and electrode, electrolyte membrane and fuel cell including the composition or polymer SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-11-03 US disclosed
US-9178218-B2 Hyper-branched polymer, electrode and electrolyte membrane including the hyper-branched polymer, and fuel cell including at least one of the electrode and the electrolyte membrane SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-11-03 US disclosed
US-20150311537-A1 COMPOSITION, POLYMER THEREOF, ELECTRODE AND ELECTROLYTE MEMBRANE FOR FUEL CELL, AND FUEL CELL INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-10-29 US disclosed
US-9168567-B2 Polymer membranes, processes for production thereof and use thereof BASF SE (DE) 2015-10-27 US disclosed
US-20110217627-A1 COMPOSITION, METHOD OF PREPARING THE COMPOSITION, ELECTRODE INCLUDING THE COMPOSITION, AND FUEL CELL INCLUDING THE ELECTRODE SAMSUNG ELECTRONICS CO., LTD. (KR) 2011-09-08 US disclosed
US-20110195338-A1 HYPER-BRANCHED POLYMER, ELECTRODE AND ELECTROLYTE MEMBRANE INCLUDING THE HYPER-BRANCHED POLYMER, AND FUEL CELL INCLUDING AT LEAST ONE OF THE ELECTRODE AND THE ELECTROLYTE MEMBRANE SAMSUNG ELECTRONICS CO., LTD. (KR) 2011-08-11 US disclosed
US-20110195340-A1 COMPOSITION, POLYMER THEREOF, ELECTRODE AND ELECTROLYTE MEMBRANE FOR FUEL CELL, AND FUEL CELL INCLUDING THE SAME SAMSUNG ELECTRONICS CO. LTD (KR) 2011-08-11 US disclosed
US-20110189581-A1 COMPOUND, CROSS-LINKED MATERIAL THEREOF, DOUBLE CROSS-LINKED POLYMER THEREOF, AND ELECTROLYTE MEMBRANE, ELECTRODE FOR FUEL CELL AND FUEL CELL INCLUDING SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2011-08-04 US disclosed
US-20100273087-A1 CROSS-LINKED POLYAZOLE, METHOD OF PREPARING THE POLYAZOLE, ELECTRODE FOR FUEL CELL INCLUDING THE CROSS-LINKED POLYAZOLE, ELECTROLYTE MEMBRANE FOR FUEL CELL INCLUDING THE CROSS-LINKED POLYAZOLE, METHOD OF MANUFACTURING THE ELECTROLYTE MEMBRANE, AND FUEL CELL INCLUDING THE CROSS-LINKED POLYAZOLE SAMSUNG ELECTRONICS CO., LTD. (KR) 2010-10-28 US disclosed
US-7745030-B2 Proton-conducting polymer membrane comprising sulfonic acid-containing polyazoles, and use thereof in fuel cells BASF FUEL CELL GMBH (DE) 2010-06-29 US disclosed
US-20100159347-A1 HYPER-BRANCHED POLYMER, ELECTRODE FOR FUEL CELL INCLUDING THE HYPER-BRANCHED POLYMER, ELECTROLYTE MEMBRANE FOR FUEL CELL INCLUDING THE HYPER-BRANCHED POLYMER, AND FUEL CELL INCLUDING AT LEAST ONE OF THE ELECTRODE AND THE ELECTROLYTE MEMBRANE SAMSUNG ELECTRONICS CO., LTD. (KR) 2010-06-24 US disclosed
US-7649025-B2 Composite ion-exchange membrane TOYO BOSEKI KABUSHIKI KAISHA (JP) 2010-01-19 US disclosed
US-7537852-B2 Composite ion exchange membrane and electrolyte membrane electrode assembly TOYO BOSEKI KABUSHIKI KAISHA (JP) 2009-05-26 US disclosed
US-20090117440-A1 BENZOXAZINE-BASED MONOMER, POLYMER THEREOF, ELECTRODE FOR FUEL CELL INCLUDING THE POLYMER, ELECTROLYTE MEMBRANE FOR FUEL CELL INCLUDING THE POLYMER, AND FUEL CELL USING THE ELECTRODE SAMSUNG ELECTRONICS CO., LTD. (KR) 2009-05-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090117440-A1 BENZOXAZINE-BASED MONOMER, POLYMER THEREOF, ELECTRODE FOR FUEL CELL INCLUDING THE POLYMER, ELECTROLYTE MEMBRANE FOR FUEL CELL INCLUDING THE POLYMER, AND FUEL CELL USING THE ELECTRODE HCN1, PXMP4, GJA1 MEN1 1762/4885KMT2A 634/4885NPC1 4547/4885
US-20150311537-A1 COMPOSITION, POLYMER THEREOF, ELECTRODE AND ELECTROLYTE MEMBRANE FOR FUEL CELL, AND FUEL CELL INCLUDING THE SAME PEF1, FERMT2, PHOSPHO1 MEN1 547/4885KMT2A 1609/4885NPC1 2414/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.