Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 5/20 | 0.40 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15835815 | 0.97 | ENPP2 (0.41) | ENPP2PHLPP2THRBCA2CA3 | |
| SCHEMBL15835809 | 0.95 | ENPP2 (0.38) | ENPP2PHLPP2THRBCA2CA3 | |
| SCHEMBL15835813 | 0.92 | PHLPP2 (0.42) | ENPP2PHLPP2THRBMAPTMAPK1 | |
| SCHEMBL16309282 | 0.91 | ENPP2 (0.43) | ENPP2PHLPP2THRBCA2CA3 | |
| SCHEMBL15835811 | 0.90 | PHLPP2 (0.36) | ENPP2PHLPP2THRB | |
| SCHEMBL15835814 | 0.85 | PHLPP2 (0.41) | ENPP2PHLPP2THRBALDH1A1 | |
| SCHEMBL15835812 | 0.84 | PHLPP2 (0.40) | ENPP2PHLPP2THRBMAPTALDH1A1 | |
| SCHEMBL14159117 | 0.82 | PHLPP2 (0.52) | ENPP2PHLPP2THRBMAPTALDH1A1 | |
| SCHEMBL14134072 | 0.82 | ENPP2 (0.36) | ENPP2PHLPP2 | |
| SCHEMBL14159105 | 0.81 | PHLPP2 (0.53) | ENPP2PHLPP2THRBMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140173835-A1 | Mixtures of Reactive Dyes and Their Use | HUNTSMAN INTERNATIONAL LLC (US) | 2014-06-26 | — | — | US | disclosed |