Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 3/20 | 0.40 |
| ▸ | ADH1A | P07327 | 3/20 | 0.40 |
| ▸ | ADH1C | P00326 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ADH7 | P40394 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5878845 | 0.82 | ADH1B (0.41) | ADH1BADH1AADH1CKDM4EADH7 | |
| SCHEMBL5878451 | 0.82 | ADH1B (0.44) | ADH1BADH1AADH1CKDM4EADH7 | |
| SCHEMBL25599131 | 0.78 | KDM4E (0.48) | KDM4E | |
| SCHEMBL15835860 | 0.77 | ADH1B (0.36) | ADH1BADH1AADH1CKDM4EADH7 | |
| SCHEMBL15835912 | 0.75 | CARM1 (0.34) | KDM4E | |
| SCHEMBL1002824 | 0.74 | — | — | |
| SCHEMBL23766640 | 0.73 | ADH1B (0.52) | ADH1BADH1AADH1CKDM4EADH7 | |
| SCHEMBL15509645 | 0.73 | KDM4E (0.35) | KDM4E | |
| SCHEMBL15830171 | 0.73 | NPC1 (0.32) | KDM4E | |
| SCHEMBL15830358 | 0.73 | NPC1 (0.32) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014100764-A2 | METHODS OF INHIBITING PRMT5 | Epizyme, Inc. (US) | 2014-06-26 | — | — | WO | disclosed |