SCHEMBL1583643

SCHEMBL1583643

C#CN(CC(C)C)CC(C)C

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.36
MAPK1 P28482 1/20 0.36
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26032545 0.77
SCHEMBL4738365 0.73
SCHEMBL269710 0.69 CYP1A2 (0.36) CYP1A2MAPK1CA12CA1CA2
SCHEMBL3970837 0.69 CYP1A2 (0.36) CYP1A2MAPK1CA12CA1CA2
SCHEMBL10703683 0.69 CYP1A2 (0.48) CYP1A2MAPK1CA12CA1CA2
SCHEMBL270802 0.69 CA12 (0.36) CYP1A2MAPK1CA12CA1CA2
SCHEMBL65000 0.68 CYP1A2 (0.53) CYP1A2MAPK1CA12CA1CA2
SCHEMBL1583184 0.67 CYP1A2 (0.35) CYP1A2MAPK1
Ammonia Solution, Strong SCHEMBL5964780 0.65 CYP1A2 (0.50) CYP1A2MAPK1CA12CA1CA2
SCHEMBL8021435 0.65 CYP1A2 (0.50) CYP1A2MAPK1CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1647555-B1 THE C-GLYCOSYLISOFLAVONES HAVING ALKYLAMINOALKOXYL SUBSTITUENT, THE PREPARATION AND THE USE OF THE SAME INST RADIATION MED AMMS PLA (CN) 2011-04-20 EP claimed
EP-1417190-B1 SUBSTITUTED PIPERAZINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR AMGEN INC (US) 2008-10-22 EP claimed
EP-1416933-B1 SUBSTITUTED PIPERIDINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR AMGEM INC (US) 2008-01-02 EP claimed
WO-1997020641-A1 METHOD FOR PROTECTING A METAL PART FROM CORROSION AND/OR PREPARING IT FOR SHAPING SOLLAC S.A. (FR) 1997-06-12 WO claimed