SCHEMBL1583773

SCHEMBL1583773

O=S(O)c1ccc2ccccc2c1.[NaH]

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.45
MAPT P10636 2/20 0.45
LMNA P02545 2/20 0.45
HTT P42858 1/20 0.45
GFER P55789 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
CES2 O00748 1/20 0.43
CES1 P23141 1/20 0.43
CYP1A2 P05177 2/20 0.43
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CYP2A6 P11509 4/20 0.38
CYP3A4 P08684 2/20 0.38
HSD17B10 Q99714 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
GSTP1 P09211 1/20 0.38
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16938449 0.98 ALDH1A1 (0.46) ALDH1A1MAPTLMNAHTTGFER
SCHEMBL29988400 0.98 ALDH1A1 (0.46) ALDH1A1MAPTLMNAHTTGFER
SCHEMBL664585 0.98 ALDH1A1 (0.46) ALDH1A1MAPTLMNAHTTGFER
SCHEMBL3152266 0.96 ALDH1A1 (0.45) ALDH1A1MAPTLMNAHTTGFER
SCHEMBL11335899 0.96 ALDH1A1 (0.45) ALDH1A1MAPTLMNAHTTGFER
Formaldehyde SCHEMBL1883227 0.96 ALDH1A1 (0.45) ALDH1A1MAPTLMNAHTTGFER
Ammonia Solution, Strong SCHEMBL3156815 0.96 ALDH1A1 (0.45) ALDH1A1MAPTLMNAHTTGFER
SCHEMBL27279294 0.88 ESR1 (0.50) ALDH1A1MAPTLMNAHTTGFER
SCHEMBL3151975 0.84 SLC6A4 (0.40) ALDH1A1MAPTLMNAHTTGFER
SCHEMBL4649800 0.82 ALDH1A1 (0.37) ALDH1A1MAPTLMNAHTTGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103922976-B Asymmetry diaryl sulfone compounds and preparation method thereof 绍兴文理学院 2016-08-17 CN claimed
CN-103922976-A Asymmetric diaryl sulfone compound and preparation method thereof UNIV SHAOXING 2014-07-16 CN claimed
US-20240148613-A1 DENTAL POLYMERIZATION KIT SUN MEDICAL CO., LTD. (JP) 2024-05-09 US disclosed
EP-4316453-A1 DENTAL POLYMERIZATION KIT Sun Medical Co., Ltd. (JP) 2024-02-07 EP disclosed
US-11844847-B2 Sulfur-containing polymerizable monomer and use thereof SUN MEDICAL CO., LTD. (JP) 2023-12-19 US disclosed
CN-116113436-A Systems and methods for protecting nucleic acid molecules 斯坦福大学托管董事会 2023-05-12 CN disclosed
CN-113387855-B Method for synthesizing disulfide compound by visible light and titanocene complex concerted catalysis 陕西师范大学 2023-04-14 CN disclosed
CN-115197108-A Preparation method of gamma-ketosulfone compound 南华大学 2022-10-18 CN disclosed
CN-114478371-A Application of nickel/ketone double-catalysis system in cross-coupling reaction of halogenated aromatic hydrocarbon and sodium arylsulfinate 苏州大学 2022-05-13 CN disclosed
US-20210298997-A1 SULFUR-CONTAINING POLYMERIZABLE MONOMER AND USE THEREOF SUN MEDICAL CO., LTD. (JP) 2021-09-30 US disclosed
CN-113387855-A Method for synthesizing disulfide compound by using visible light and titanocene complex under concerted catalysis 陕西师范大学 2021-09-14 CN disclosed
EP-0880502-A1 AMINOHETEROCYCLIC DERIVATIVES AS ANTITHROMBOTIC OR ANTICOAGULANT AGENTS ZENECA LIMITED (GB) 1998-12-02 EP disclosed
EP-0783500-B1 AMINOHETEROCYCLIC DERIVATIVES AS ANTITHROMBOTIC OR ANTICOAGULANT AGENTS ZENECA LTD (GB) 1998-07-22 EP disclosed
WO-1997028129-A1 AMINOHETEROCYCLIC DERIVATIVES AS ANTITHROMBOTIC OR ANTICOAGULANT AGENTS ZENECA LIMITED (GB) 1997-08-07 WO disclosed
EP-0783500-A1 AMINOHETEROCYCLIC DERIVATIVES AS ANTITHROMBOTIC OR ANTICOAGULANT AGENTS ZENECA LIMITED (GB) 1997-07-16 EP disclosed
US-5605918-A SUBSTITUTED THIAZOLIDINE-2,4-DIONES AMERICAN HOME PRODUCTS CORPORATION (US) 1997-02-25 US disclosed
EP-0749430-A1 THIAZOLIDINEDIONE DERIVATIVES AS ANTI-HYPERGLYCEMIC AGENTS AMERICAN HOME PRODUCTS CORPORATION (US) 1996-12-27 EP disclosed
US-5574051-A HYPOGLYCEMIC AMERICAN HOME PRODUCTS CORPORATION (US) 1996-11-12 US disclosed
WO-1996010022-A1 AMINOHETEROCYCLIC DERIVATIVES AS ANTITHROMBOTIC OR ANTICOAGULANT AGENTS ZENECA LIMITED (GB) 1996-04-04 WO disclosed
WO-1995024400-A1 THIAZOLIDINEDIONE DERIVATIVES AS ANTI-HYPERGLYCEMIC AGENTS AMERICAN HOME PRODUCTS CORPORATION (US) 1995-09-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210298997-A1 SULFUR-CONTAINING POLYMERIZABLE MONOMER AND USE THEREOF MGMT, SETDB1, ASH2L ALDH1A1 2202/4885MAPT 1453/4885LMNA 2881/4885
US-11844847-B2 Sulfur-containing polymerizable monomer and use thereof MGMT, SETDB1, ASH2L ALDH1A1 2202/4885MAPT 1453/4885LMNA 2881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.