Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1583786 | 1.00 | CHRM2 (0.47) | CHRM2CHRM1CHRM3PREPNR1H2 | |
| SCHEMBL1662768 | 0.93 | NR1H2 (0.40) | CHRM2CHRM1CHRM3PREPNR1H2 | |
| SCHEMBL1583749 | 0.93 | NR1H2 (0.40) | CHRM2CHRM1CHRM3PREPNR1H2 | |
| SCHEMBL2322107 | 0.86 | CHRM2 (0.51) | CHRM2CHRM1CHRM3PREPNR1H2 | |
| SCHEMBL1664180 | 0.86 | CHRM2 (0.51) | CHRM2CHRM1CHRM3PREPNR1H2 | |
| SCHEMBL1583351 | 0.84 | CHRM2 (0.49) | CHRM2CHRM1CHRM3PREPNR1H2 | |
| SCHEMBL1663196 | 0.84 | CHRM2 (0.49) | CHRM2CHRM1CHRM3PREPNR1H2 | |
| SCHEMBL1583349 | 0.84 | CHRM2 (0.49) | CHRM2CHRM1CHRM3PREPNR1H2 | |
| SCHEMBL5619854 | 0.84 | CHRM2 (0.46) | CHRM2CHRM1CHRM3PREPNR1H2 | |
| SCHEMBL1584022 | 0.82 | NR1H2 (0.53) | CHRM2CHRM1CHRM3NR1H2DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011041713-A2 | PIPERAZINYL ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-07 | — | — | WO | disclosed |