Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.51 |
| ▸ | PREP | P48147 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2322107 | 1.00 | CHRM2 (0.51) | CHRM2CHRM1CHRM3PREPMAPT | |
| SCHEMBL1583351 | 0.93 | CHRM2 (0.49) | CHRM2CHRM1CHRM3PREPMAPT | |
| SCHEMBL1583349 | 0.93 | CHRM2 (0.49) | CHRM2CHRM1CHRM3PREPMAPT | |
| SCHEMBL1663196 | 0.93 | CHRM2 (0.49) | CHRM2CHRM1CHRM3PREPMAPT | |
| SCHEMBL5619854 | 0.90 | CHRM2 (0.46) | CHRM2CHRM1CHRM3PREPMAPT | |
| SCHEMBL1583786 | 0.86 | CHRM2 (0.47) | CHRM2CHRM1CHRM3PREPMAPT | |
| SCHEMBL1583785 | 0.86 | CHRM2 (0.47) | CHRM2CHRM1CHRM3PREPMAPT | |
| SCHEMBL1583626 | 0.85 | NR1H2 (0.50) | CHRM2CHRM1CHRM3PREPMAPT | |
| SCHEMBL1583858 | 0.85 | TP53 (0.44) | CHRM2CHRM1CHRM3PREPMAPT | |
| SCHEMBL3069589 | 0.84 | EPHX1 (0.47) | CHRM2CHRM1CHRM3PREPMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050284-A1 | PYRAZOLYLPYRIDINE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |