Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17208430 | 0.90 | EPHX2 (0.51) | EPHX2CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL15840440 | 0.88 | EPHX2 (0.48) | EPHX2 | |
| SCHEMBL15840481 | 0.88 | EPHX2 (0.48) | EPHX2 | |
| SCHEMBL15840447 | 0.86 | NPC1 (0.49) | EPHX2 | |
| SCHEMBL15840441 | 0.86 | NAMPT (0.50) | — | |
| SCHEMBL15840476 | 0.86 | MCHR1 (0.54) | — | |
| SCHEMBL22059969 | 0.86 | EPHX2 (0.52) | EPHX2CNR1 | |
| SCHEMBL15840489 | 0.86 | NPC1 (0.57) | — | |
| SCHEMBL15840485 | 0.85 | DRD2 (0.54) | EPHX2 | |
| SCHEMBL20744371 | 0.84 | EPHX2 (0.51) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9957249-B2 | Saturated nitrogen and N-acylated heterocycles potentiating the activity of an active antibiotic against Mycobacteria | UNIVERSITE DE DROIT ET DE LA SANTE DE LILLE 2 (FR) | 2018-05-01 | — | — | US | disclosed |
| US-9957249-B2 | Saturated nitrogen and N-acylated heterocycles potentiating the activity of an active antibiotic against Mycobacteria | UNIVERSITE DE DROIT ET DE LA SANTE DE LILLE 2 (FR) | 2018-05-01 | — | — | US | disclosed |
| US-20150307471-A1 | Saturated Nitrogen and N-Acylated Heterocycles Potentiating the Activity of an Active Antibiotic against Mycobacteria | UNIVERSITE DE DROIT ET DE LA SANTE DE LILLE 2 (FR) | 2015-10-29 | — | — | US | disclosed |
| US-20150307471-A1 | Saturated Nitrogen and N-Acylated Heterocycles Potentiating the Activity of an Active Antibiotic against Mycobacteria | UNIVERSITE DE DROIT ET DE LA SANTE DE LILLE 2 (FR) | 2015-10-29 | — | — | US | disclosed |
| WO-2014096378-A1 | SATURATED NITROGEN AND N-ACYLATED HETEROCYCLES POTENTIATING THE ACTIVITY OF AN ACTIVE ANTIBIOTIC AGAINST MYCOBACTERIA | UNIVERSITE DE DROIT ET DE LA SANTE DE LILLE 2 (FR) | 2014-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150307471-A1 | Saturated Nitrogen and N-Acylated Heterocycles Potentiating the Activity of an Active Antibiotic against Mycobacteria | NAT1, NAA15, FNTB | EPHX2 4354/4885CHRM2 1192/4885CHRM5 973/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.