Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | TACR3 | P29371 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.58 |
| ▸ | HTR2B | P41595 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MGLL | Q99685 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | FAAH | O00519 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17208440 | 0.90 | NPC1 (0.58) | NPC1TACR3CYP2C9CYP2C19MAPK14 | |
| Carbamic Acid SCHEMBL27008248 | 0.83 | ALDH1A1 (0.57) | NPC1TACR3CYP2C9CYP2C19MAPK14 | |
| SCHEMBL18435561 | 0.83 | POLB (0.71) | NPC1TACR3ALDH1A1RAB9AMEN1 | |
| SCHEMBL23682656 | 0.83 | TACR3 (0.83) | TACR3ALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL15840489 | 0.81 | NPC1 (0.57) | NPC1ALDH1A1POLB | |
| SCHEMBL4768006 | 0.80 | CYP2C9 (0.64) | TACR3CYP2C9CYP2C19MAPK14HTR2B | |
| SCHEMBL19233533 | 0.80 | MEN1 (0.68) | TACR3CYP2C9CYP2C19MAPK14HTR2B | |
| SCHEMBL7362106 | 0.79 | ALDH1A1 (0.64) | TACR3CYP2C9CYP2C19MAPK14HTR2B | |
| SCHEMBL2243090 | 0.79 | ALDH1A1 (0.64) | TACR3CYP2C9CYP2C19MAPK14HTR2B | |
| SCHEMBL6485095 | 0.79 | ALDH1A1 (0.64) | TACR3CYP2C9CYP2C19MAPK14HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9957249-B2 | Saturated nitrogen and N-acylated heterocycles potentiating the activity of an active antibiotic against Mycobacteria | UNIVERSITE DE DROIT ET DE LA SANTE DE LILLE 2 (FR) | 2018-05-01 | — | — | US | disclosed |
| US-9957249-B2 | Saturated nitrogen and N-acylated heterocycles potentiating the activity of an active antibiotic against Mycobacteria | UNIVERSITE DE DROIT ET DE LA SANTE DE LILLE 2 (FR) | 2018-05-01 | — | — | US | disclosed |
| US-20150307471-A1 | Saturated Nitrogen and N-Acylated Heterocycles Potentiating the Activity of an Active Antibiotic against Mycobacteria | UNIVERSITE DE DROIT ET DE LA SANTE DE LILLE 2 (FR) | 2015-10-29 | — | — | US | disclosed |
| US-20150307471-A1 | Saturated Nitrogen and N-Acylated Heterocycles Potentiating the Activity of an Active Antibiotic against Mycobacteria | UNIVERSITE DE DROIT ET DE LA SANTE DE LILLE 2 (FR) | 2015-10-29 | — | — | US | disclosed |
| WO-2014096378-A1 | SATURATED NITROGEN AND N-ACYLATED HETEROCYCLES POTENTIATING THE ACTIVITY OF AN ACTIVE ANTIBIOTIC AGAINST MYCOBACTERIA | UNIVERSITE DE DROIT ET DE LA SANTE DE LILLE 2 (FR) | 2014-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150307471-A1 | Saturated Nitrogen and N-Acylated Heterocycles Potentiating the Activity of an Active Antibiotic against Mycobacteria | NAT1, NAA15, FNTB | NPC1 40/4885TACR3 1662/4885CYP2C9 714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.