Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 17/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17208425 | 0.90 | RBP4 (0.70) | RBP4CYP2D6CYP2C19 | |
| SCHEMBL31613472 | 0.87 | RBP4 (0.73) | RBP4CYP2D6CYP2C19 | |
| SCHEMBL16118452 | 0.87 | RBP4 (0.81) | RBP4CYP2D6CYP2C19 | |
| SCHEMBL15840448 | 0.86 | RBP4 (0.53) | RBP4 | |
| SCHEMBL15840438 | 0.86 | RBP4 (0.53) | RBP4 | |
| SCHEMBL15840445 | 0.85 | RBP4 (0.52) | RBP4 | |
| SCHEMBL15840439 | 0.85 | TRPV1 (0.55) | RBP4 | |
| SCHEMBL20419358 | 0.85 | RBP4 (0.77) | RBP4CYP2D6CYP2C19 | |
| SCHEMBL29596961 | 0.84 | RBP4 (1.00) | RBP4CYP2D6CYP2C19 | |
| SCHEMBL17505321 | 0.84 | RBP4 (1.00) | RBP4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9957249-B2 | Saturated nitrogen and N-acylated heterocycles potentiating the activity of an active antibiotic against Mycobacteria | UNIVERSITE DE DROIT ET DE LA SANTE DE LILLE 2 (FR) | 2018-05-01 | — | — | US | disclosed |
| US-9957249-B2 | Saturated nitrogen and N-acylated heterocycles potentiating the activity of an active antibiotic against Mycobacteria | UNIVERSITE DE DROIT ET DE LA SANTE DE LILLE 2 (FR) | 2018-05-01 | — | — | US | disclosed |
| US-20150307471-A1 | Saturated Nitrogen and N-Acylated Heterocycles Potentiating the Activity of an Active Antibiotic against Mycobacteria | UNIVERSITE DE DROIT ET DE LA SANTE DE LILLE 2 (FR) | 2015-10-29 | — | — | US | disclosed |
| US-20150307471-A1 | Saturated Nitrogen and N-Acylated Heterocycles Potentiating the Activity of an Active Antibiotic against Mycobacteria | UNIVERSITE DE DROIT ET DE LA SANTE DE LILLE 2 (FR) | 2015-10-29 | — | — | US | disclosed |
| WO-2014096378-A1 | SATURATED NITROGEN AND N-ACYLATED HETEROCYCLES POTENTIATING THE ACTIVITY OF AN ACTIVE ANTIBIOTIC AGAINST MYCOBACTERIA | UNIVERSITE DE DROIT ET DE LA SANTE DE LILLE 2 (FR) | 2014-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150307471-A1 | Saturated Nitrogen and N-Acylated Heterocycles Potentiating the Activity of an Active Antibiotic against Mycobacteria | NAT1, NAA15, FNTB | RBP4 4879/4885CYP2D6 603/4885CYP2C19 417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.