Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 4/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | XBP1 | P17861 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | CLK1 | P49759 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | STAT3 | P40763 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15840713 | 0.92 | MAPT (0.79) | MAPTALDH1A1HSD17B10SMN1; SMN2RAB9A | |
| SCHEMBL15840828 | 0.89 | MAPT (0.66) | MAPTALDH1A1HSD17B10SMN1; SMN2RAB9A | |
| SCHEMBL15840614 | 0.87 | MAPT (0.64) | MAPTALDH1A1HSD17B10SMN1; SMN2RAB9A | |
| SCHEMBL15840677 | 0.86 | MAPT (0.69) | MAPTALDH1A1HSD17B10SMN1; SMN2RAB9A | |
| SCHEMBL2465457 | 0.86 | ALDH1A1 (0.77) | MAPTALDH1A1HSD17B10SMN1; SMN2RAB9A | |
| SCHEMBL15840752 | 0.83 | CREBBP (0.74) | MAPTALDH1A1HSD17B10SMN1; SMN2RAB9A | |
| SCHEMBL23657581 | 0.83 | ALDH1A1 (0.60) | MAPTALDH1A1HSD17B10SMN1; SMN2RAB9A | |
| SCHEMBL5991672 | 0.83 | MAPT (0.66) | MAPTALDH1A1HSD17B10SMN1; SMN2RAB9A | |
| SCHEMBL15840748 | 0.83 | MAPT (0.75) | MAPTALDH1A1HSD17B10SMN1; SMN2RAB9A | |
| SCHEMBL15840758 | 0.82 | MAPT (1.00) | MAPTALDH1A1HSD17B10SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140179681-A1 | METHODS AND COMPOSITIONS OF TARGETED DRUG DEVELOPMENT | Errico, Joseph P. (US) | 2014-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140179681-A1 | METHODS AND COMPOSITIONS OF TARGETED DRUG DEVELOPMENT | EGFR, ERBB2, ERBB3 | MAPT 1076/4885ALDH1A1 4348/4885HSD17B10 2391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.