Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.41 |
| ▸ | TOP1 | P11387 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28074963 | 1.00 | TDP1 (0.71) | TDP1LMNAL3MBTL1KDM4EPDE4A | |
| SCHEMBL7123818 | 1.00 | TDP1 (0.71) | TDP1LMNAL3MBTL1KDM4EPDE4A | |
| SCHEMBL18076293 | 1.00 | TDP1 (0.71) | TDP1LMNAL3MBTL1KDM4EPDE4A | |
| SCHEMBL15804390 | 0.97 | LMNA (0.69) | TDP1LMNAL3MBTL1KDM4EPDE4A | |
| SCHEMBL14199676 | 0.97 | LMNA (0.69) | TDP1LMNAL3MBTL1KDM4EPDE4A | |
| SCHEMBL12153722 | 0.97 | LMNA (0.69) | TDP1LMNAL3MBTL1KDM4EPDE4A | |
| SCHEMBL15895192 | 0.97 | LMNA (0.69) | TDP1LMNAL3MBTL1KDM4EPDE4A | |
| SCHEMBL16748074 | 0.97 | LMNA (0.69) | TDP1LMNAL3MBTL1KDM4EPDE4A | |
| SCHEMBL14147720 | 0.97 | LMNA (0.69) | TDP1LMNAL3MBTL1KDM4EPDE4A | |
| SCHEMBL17528489 | 0.97 | LMNA (0.69) | TDP1LMNAL3MBTL1KDM4EPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9266949-B2 | Low acidic species compositions and methods for producing and using the same | ABBVIE, INC. (US) | 2016-02-23 | — | — | US | disclosed |
| US-20160038404-A1 | Anti-Malarial Pharmaceutical Composition | PROTOPHARMA LIMITED (GB) | 2016-02-11 | — | — | US | disclosed |
| US-20150259410-A1 | LOW ACIDIC SPECIES COMPOSITIONS AND METHODS FOR PRODUCING AND USING THE SAME | ABBVIE INC. | 2015-09-17 | — | — | US | disclosed |
| US-20150140006-A1 | LOW ACIDIC SPECIES COMPOSITIONS AND METHODS FOR PRODUCING AND USING THE SAME | ABBVIE INC. | 2015-05-21 | — | — | US | disclosed |
| US-20150132801-A1 | LOW ACIDIC SPECIES COMPOSITIONS AND METHODS FOR PRODUCING AND USING THE SAME | ABBVIE INC. | 2015-05-14 | — | — | US | disclosed |
| US-20140179772-A1 | Anti-Malarial Pharmaceutical Composition | PROTOPHARMA LIMITED (GB) | 2014-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150140006-A1 | LOW ACIDIC SPECIES COMPOSITIONS AND METHODS FOR PRODUCING AND USING THE SAME | ACP1, TNF, FCGR2A | TDP1 4499/4885LMNA 2870/4885L3MBTL1 3547/4885 |
| US-20150259410-A1 | LOW ACIDIC SPECIES COMPOSITIONS AND METHODS FOR PRODUCING AND USING THE SAME | ACP1, TNF, FCGR2A | TDP1 4499/4885LMNA 2870/4885L3MBTL1 3547/4885 |
| US-20150132801-A1 | LOW ACIDIC SPECIES COMPOSITIONS AND METHODS FOR PRODUCING AND USING THE SAME | ACP1, TNF, FCGR2A | TDP1 4499/4885LMNA 2870/4885L3MBTL1 3547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.