⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18109781 | 0.69 | — | — | |
| SCHEMBL29104340 | 0.67 | — | — | |
| SCHEMBL3802600 | 0.67 | — | — | |
| SCHEMBL29178442 | 0.67 | — | — | |
| SCHEMBL6022382 | 0.67 | — | — | |
| SCHEMBL3475783 | 0.67 | — | — | |
| SCHEMBL8834838 | 0.65 | — | — | |
| SCHEMBL10456171 | 0.63 | — | — | |
| SCHEMBL250607 | 0.62 | — | — | |
| SCHEMBL190697 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488522-B1 | NOVEL METHOD FOR PREPARING ENTECAVIR AND INTERMEDIATE USED THEREIN | HANMI SCIENCE CO LTD (KR) | 2017-02-15 | — | — | EP | disclosed |
| US-8569491-B2 | Method for preparing entecavir and intermediate used therein | HANMI SCIENCE CO., LTD (KR) | 2013-10-29 | — | — | US | disclosed |
| EP-2488522-A2 | NOVEL METHOD FOR PREPARING ENTECAVIR AND INTERMEDIATE USED THEREIN | Hanmi Holdings Co., Ltd. (KR) | 2012-08-22 | — | — | EP | disclosed |
| US-20120202998-A1 | NOVEL METHOD FOR PREPARING ENTECAVIR AND INTERMEDIATE USED THEREIN | HANMI HOLDINGS CO., LTD. (KR) | 2012-08-09 | — | — | US | disclosed |
| WO-2011046303-A2 | NOVEL METHOD FOR PREPARING ENTECAVIR AND INTERMEDIATE USED THEREIN | HANMI HOLDINGS CO., LTD. (KR) | 2011-04-21 | — | — | WO | disclosed |