⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29178442 | 0.67 | — | — | |
| SCHEMBL1584094 | 0.67 | — | — | |
| SCHEMBL3475783 | 0.67 | — | — | |
| SCHEMBL3802600 | 0.67 | — | — | |
| SCHEMBL28734111 | 0.65 | — | — | |
| SCHEMBL2836895 | 0.65 | TSHR (0.32) | — | |
| SCHEMBL1405901 | 0.65 | — | — | |
| SCHEMBL5881324 | 0.65 | — | — | |
| SCHEMBL7257637 | 0.63 | — | — | |
| SCHEMBL18109781 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613646-A2 | PROCESS FOR PREPARATION OF CYCLOSPORIN \"A\" ANALOGUES HAVING A TERMINAL DIENE GROUP | Isotechnika Inc. (CA) | 2006-01-11 | — | — | EP | disclosed |
| US-20040220091-A1 | Process for preparation of cyclosporin A analogs | ISOTECHNIKA INC. (CA) | 2004-11-04 | — | — | US | disclosed |
| WO-2004089960-A2 | PROCESS FOR PREPARATION OF CYCLOSPORIN “A” ANALOGUES HAVING A TERMINAL DIENE GROUP | ISOTECHNIKA INC. (CA) | 2004-10-21 | — | — | WO | disclosed |