SCHEMBL1584099

SCHEMBL1584099

CCCCC[SiH2]CCl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4247522 0.97 TSHR (0.48)
SCHEMBL18048897 0.97 TSHR (0.48)
SCHEMBL27444906 0.97
SCHEMBL521412 0.81 TSHR (0.50)
SCHEMBL9191869 0.78 TSHR (0.60)
SCHEMBL31216189 0.78 TSHR (0.68)
SCHEMBL2510830 0.78 TSHR (0.57)
SCHEMBL2512253 0.78 TSHR (0.57)
SCHEMBL10841351 0.78 TSHR (0.57)
SCHEMBL10803622 0.78 TSHR (0.57)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2488522-B1 NOVEL METHOD FOR PREPARING ENTECAVIR AND INTERMEDIATE USED THEREIN HANMI SCIENCE CO LTD (KR) 2017-02-15 EP disclosed
US-8569491-B2 Method for preparing entecavir and intermediate used therein HANMI SCIENCE CO., LTD (KR) 2013-10-29 US disclosed
EP-2488522-A2 NOVEL METHOD FOR PREPARING ENTECAVIR AND INTERMEDIATE USED THEREIN Hanmi Holdings Co., Ltd. (KR) 2012-08-22 EP disclosed
US-20120202998-A1 NOVEL METHOD FOR PREPARING ENTECAVIR AND INTERMEDIATE USED THEREIN HANMI HOLDINGS CO., LTD. (KR) 2012-08-09 US disclosed
WO-2011046303-A2 NOVEL METHOD FOR PREPARING ENTECAVIR AND INTERMEDIATE USED THEREIN HANMI HOLDINGS CO., LTD. (KR) 2011-04-21 WO disclosed
US-4615706-A APPLYING TEXTILE ANTISTATIC AGENT HEATING STAUFFER-WACKER SILICONES CORPORATION (US) 1986-10-07 US disclosed
EP-0095156-B1 PROCESS FOR PREPARING QUATERNARY AMMONIUM-FUNCTIONAL SILICON COMPOUNDS, PRODUCTS PREPARED THEREOF AND USE OF THE SAME Stauffer-Wacker Silicones Corporation (US) 1986-08-13 EP disclosed
EP-0095157-B1 PROCESS FOR PREPARING QUATERNARY AMMONIUM-FUNCTIONAL SILICON COMPOUNDS, PRODUCTS PREPARED THEREOF AND USE OF THE SAME Stauffer-Wacker Silicones Corporation (US) 1986-08-06 EP disclosed
EP-0095155-B1 PROCESS FOR PREPARING QUATERNARY AMMONIUM-FUNCTIONAL SILICON COMPOUNDS, PRODUCTS PREPARED THEREOF AND USE OF THE SAME Stauffer-Wacker Silicones Corporation (US) 1986-08-06 EP disclosed
US-4511727-A FROM HYDROX-ALYKYL-SUBSITUTED POLYSILOXANE AND QUATERNARY AMMONIUM-CONTAINING CARBOXYLIC ACID SWS SILICONES CORPORATION (US) 1985-04-16 US disclosed
EP-0095155-A2 Process for preparing quaternary ammonium-functional silicon compounds, products prepared thereof and use of the same Stauffer-Wacker Silicones Corporation (US) 1983-11-30 EP disclosed
EP-0095156-A2 Process for preparing quaternary ammonium-functional silicon compounds, products prepared thereof and use of the same Stauffer-Wacker Silicones Corporation (US) 1983-11-30 EP disclosed
EP-0095157-A2 Process for preparing quaternary ammonium-functional silicon compounds, products prepared thereof and use of the same Stauffer-Wacker Silicones Corporation (US) 1983-11-30 EP disclosed
US-4394517-A CATIONIC POLYSILOXANES; ANTISTATIC AGENTS; TEXTILES SWS SILICONES CORPORATION (US) 1983-07-19 US disclosed
US-4390713-A CATIONIC POLYMERS FROM A CARBOXYLIC ACID-CONTAINING POLYSILOXANE AND A HYDROXYL-CONTAINING AMMONIUM SALT; TEXTILE ANTISTATIC AGENTS SWS SILICONES CORPORATION (US) 1983-06-28 US disclosed
US-4384130-A TEXTILE ANTISTATIC AGENTS SWS SILICONES CORPORATION (US) 1983-05-17 US disclosed
US-3963726-A Quaternary ammonium salts of chloromethylated silicon compounds UNION CARBIDE CORPORATION (US) 1976-06-15 US disclosed