Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | DNM1 | Q05193 | 9/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2511627 | 1.00 | TSHR (0.57) | TSHRTHRBDNM1ALDH1A1MEN1 | |
| SCHEMBL67826 | 1.00 | TSHR (0.57) | TSHRTHRBDNM1ALDH1A1MEN1 | |
| SCHEMBL2510830 | 1.00 | TSHR (0.57) | TSHRTHRBDNM1ALDH1A1MEN1 | |
| SCHEMBL16209849 | 1.00 | TSHR (0.57) | TSHRTHRBDNM1ALDH1A1MEN1 | |
| SCHEMBL17386447 | 1.00 | TSHR (0.57) | TSHRTHRBDNM1ALDH1A1MEN1 | |
| SCHEMBL10803622 | 1.00 | TSHR (0.57) | TSHRTHRBDNM1ALDH1A1MEN1 | |
| SCHEMBL181208 | 1.00 | TSHR (0.57) | TSHRTHRBDNM1ALDH1A1MEN1 | |
| SCHEMBL17386495 | 1.00 | TSHR (0.57) | TSHRTHRBDNM1ALDH1A1MEN1 | |
| SCHEMBL10841351 | 1.00 | TSHR (0.57) | TSHRTHRBDNM1ALDH1A1MEN1 | |
| SCHEMBL3397735 | 1.00 | TSHR (0.57) | TSHRTHRBDNM1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2915824-B1 | METALLOCENE LIGANDS, METALLOCENE COMPOUNDS AND METALLOCENE CATALYSTS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS | LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) | 2022-05-25 | — | — | EP | claimed |
| EP-2915824-A1 | METALLOCENE LIGANDS, METALLOCENE COMPOUNDS AND METALLOCENE CATALYSTS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS | Lummus Novolen Technology Gmbh (DE) | 2015-09-09 | — | — | EP | claimed |
| CN-101124252-B | Metallocene catalysts, their synthesis and use in olefin polymerization | NOVOLEN TECH HOLDINGS CV | 2011-10-05 | — | — | CN | claimed |
| CN-1946748-B | Metallocene ligands, metallocene compounds and metallocene catalysts, their synthesis and their use for the polymerization of olefins | NOVOLEN TECH HOLDINGS CV | 2011-04-06 | — | — | CN | claimed |
| CN-101124252-A | Metallocene catalysts, their synthesis and use in olefin polymerization | NOVOLEN TECH HOLDINGS CV (NL) | 2008-02-13 | — | — | CN | claimed |
| JP-2007534703-A | — | — | 2007-11-29 | — | — | JP | claimed |
| US-7285608-B2 | Metallocene ligands, metallocene compounds and metallocene catalysts, their synthesis and their use for the polymerization of olefins | NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) | 2007-10-23 | — | — | US | claimed |
| EP-1828266-A1 | METALLOCENE CATALYSTS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS | Novolen Technology Holdings, C.V. (NL) | 2007-09-05 | — | — | EP | claimed |
| CN-1946748-A | Metallocene ligands, metallocene compounds and metallocene catalysts, their synthesis and their use for the polymerization of olefins | NOVOLEN TECH HOLDINGS CV (NL) | 2007-04-11 | — | — | CN | claimed |
| US-7169864-B2 | Loeading and heating a catalyst support with an alumoxane and further loading with a Group IVB metallocene and a second aluminoxane cocatalyst alone or in combination with a Lewis Acid or ionic compound; improved catalyst selectivity and polymerization efficiency | NOVOLEN TECHNOLOGY HOLDINGS, C.V. (NL) | 2007-01-30 | — | — | US | claimed |
| EP-1740622-A2 | METALLOCENE LIGANDS, METALLOCENE COMPOUNDS AND METALLOCENE CATALYSTS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS | Novolen Technology Holdings C.V. (NL) | 2007-01-10 | — | — | EP | claimed |
| WO-2006060544-A1 | METALLOCENE CATALYSTS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS | NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) | 2006-06-08 | — | — | WO | claimed |
| US-20060116490-A1 | Metallocene catalysts, their synthesis and their use for the polymerization of olefins | LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) | 2006-06-01 | — | — | US | claimed |
| WO-2005105863-A2 | METALLOCENE LIGANDS, METALLOCENE COMPOUNDS AND METALLOCENE CATALYSTS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS | NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) | 2005-11-10 | — | — | WO | claimed |
| US-20050239979-A1 | Metallocene ligands, metallocene compounds and metallocene catalysts, their synthesis and their use for the polymerization of olefins | LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) | 2005-10-27 | — | — | US | claimed |
| US-11312633-B2 | Silicon-carbon composite powder | EVONIK OPERATIONS GMBH (DE) | 2022-04-26 | — | — | US | disclosed |
| CN-107406476-B | Mononuclear iron complex and organic synthesis reaction using same | 国立大学法人九州大学 | 2021-07-27 | — | — | CN | disclosed |
| US-5223344-A | Containing silicon hydrides; coatings | GENERAL ELECTRIC COMPANY (US) | 1993-06-29 | — | — | US | disclosed |
| US-5161039-A | Birefringent structures formed by photo-exposure of polymer films and method for fabrication thereof | BOARD OF TRUSTEES, LELAND STANFORD JR. UNIVERSITY (US) | 1992-11-03 | — | — | US | disclosed |
| US-5105298-A | Birefringent structures formed by photo-exposure of polymer films and method for fabrication thereof | BOARD OF TRUSTEES, LELAND STANFORD JR. UNIVERSITY (US) | 1992-04-14 | — | — | US | disclosed |