Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15845074 | 0.96 | KMT2A (0.46) | TSHRCYP3A4TP53MAPK1ALDH1A1 | |
| SCHEMBL15844998 | 0.89 | TSHR (0.44) | TSHRCYP3A4TP53MAPK1ALDH1A1 | |
| SCHEMBL218327 | 0.86 | TSHR (0.45) | TSHRCYP3A4TP53MAPK1ALDH1A1 | |
| SCHEMBL29378202 | 0.86 | TSHR (0.45) | TSHRCYP3A4TP53MAPK1ALDH1A1 | |
| SCHEMBL29727362 | 0.86 | TSHR (0.62) | TSHRCYP3A4TP53MAPK1ALDH1A1 | |
| SCHEMBL14197615 | 0.86 | TSHR (0.62) | TSHRCYP3A4TP53MAPK1ALDH1A1 | |
| SCHEMBL276086 | 0.85 | SERPINE1 (0.50) | TDP1SERPINE1 | |
| SCHEMBL12938315 | 0.84 | ESR1 (0.49) | TSHRCYP3A4ALDH1A1TDP1SERPINE1 | |
| SCHEMBL3651606 | 0.83 | HTT (0.43) | TSHRCYP3A4TP53MAPK1ALDH1A1 | |
| SCHEMBL27096682 | 0.82 | TSHR (0.49) | TSHRCYP3A4TP53MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9348228-B2 | Acid-strippable silicon-containing antireflective coating | GLOBALFOUNDRIES INC. (KY) | 2016-05-24 | — | — | US | disclosed |
| WO-2014107476-A1 | ACID-STRIPPABLE SILICON-CONTAINING ANTIREFLECTIVE COATING | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2014-07-10 | — | — | WO | disclosed |
| US-20140186774-A1 | ACID-STRIPPABLE SILICON-CONTAINING ANTIREFLECTIVE COATING | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2014-07-03 | — | — | US | disclosed |