Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.67 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 3/20 | 0.44 |
| ▸ | RXRB | P28702 | 3/20 | 0.44 |
| ▸ | RXRG | P48443 | 3/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | SLC26A3 | P40879 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1584592 | 0.92 | SLC22A12 (0.66) | SLC22A12CA5ARXRARXRBRXRG | |
| SCHEMBL1584507 | 0.86 | SLC22A12 (0.72) | SLC22A12CA5ARXRARXRBRXRG | |
| SCHEMBL1584528 | 0.83 | SLC22A12 (0.74) | SLC22A12CA5ARXRARXRBRXRG | |
| SCHEMBL460443 | 0.81 | SLC22A12 (1.00) | SLC22A12RXRARXRBRXRGFFAR4 | |
| SCHEMBL1584983 | 0.74 | SLC22A12 (0.54) | SLC22A12GAAALDH1A1MEN1KMT2A | |
| SCHEMBL7897205 | 0.73 | SLC22A12 (0.67) | SLC22A12CA5ARXRARXRBRXRG | |
| SCHEMBL955065 | 0.73 | SLC22A12 (0.78) | SLC22A12CA5ARXRARXRBRXRG | |
| SCHEMBL17316708 | 0.71 | SLC22A12 (0.60) | SLC22A12CA5ARXRARXRBRXRG | |
| SCHEMBL334173 | 0.71 | SLC22A12 (0.63) | SLC22A12CA5ARXRARXRBRXRG | |
| SCHEMBL956632 | 0.70 | SLC22A12 (0.78) | SLC22A12RXRARXRBRXRGFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488020-B1 | 3-SUBSTITUTED COMPOUNDS FOR REDUCING URIC ACID | WELLSTAT THERAPEUTICS CORP (US) | 2016-12-14 | — | — | EP | disclosed |
| EP-2488020-A1 | 3-SUBSTITUTED COMPOUNDS FOR REDUCING URIC ACID | Wellstat Therapeutics Corporation (US) | 2012-08-22 | — | — | EP | disclosed |
| WO-2011046800-A1 | 3-SUBSTITUTED COMPOUNDS FOR REDUCING URIC ACID | WELLSTAT THERAPEUTICS CORPORATION (US) | 2011-04-21 | — | — | WO | disclosed |