Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 4/20 | 0.54 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KDM5A | P29375 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15846311 | 0.90 | MEN1 (0.50) | HIF1AEGLN1MEN1KMT2AKDM4E | |
| SCHEMBL15846650 | 0.89 | SERPINE1 (0.50) | HIF1AMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL15846255 | 0.89 | KDM4E (0.51) | HIF1AMEN1KMT2AKDM4ERXFP1 | |
| SCHEMBL15846617 | 0.89 | KMT2A (0.48) | HIF1AEGLN1MEN1KMT2AKDM4E | |
| SCHEMBL15847122 | 0.88 | KDM4E (0.50) | HIF1AMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL15845956 | 0.87 | SERPINE1 (0.49) | HIF1AMEN1KMT2AKDM4ERXFP1 | |
| SCHEMBL5310233 | 0.87 | HIF1A (0.52) | HIF1AMEN1KMT2AKDM4ETDP1 | |
| SCHEMBL15846147 | 0.86 | KMT2A (0.46) | HIF1AMEN1KMT2AKDM4ERXFP1 | |
| SCHEMBL15846209 | 0.85 | KDM4E (0.47) | HIF1AMEN1KMT2AKDM4ERXFP1 | |
| SCHEMBL5308306 | 0.84 | KDM4E (0.53) | EGLN1MEN1KMT2AKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935221-A1 | NOVEL QUINOLONE DERIVATIVES | Cadila Healthcare Limited (IN) | 2015-10-28 | — | — | EP | disclosed |
| WO-2014102818-A1 | NOVEL QUINOLONE DERIVATIVES | CADILA HEALTHCARE LIMITED (IN) | 2014-07-03 | — | — | WO | disclosed |