Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5309948 | 0.89 | MEN1 (0.61) | MEN1KMT2ARXFP1TDP1NPC1 | |
| SCHEMBL5305542 | 0.87 | MEN1 (0.54) | MEN1KMT2ARXFP1TDP1NPC1 | |
| SCHEMBL15845971 | 0.87 | HIF1A (0.54) | HIF1AMEN1KMT2ARXFP1TDP1 | |
| SCHEMBL5309416 | 0.85 | MEN1 (0.52) | MEN1KMT2ARXFP1TDP1NPC1 | |
| SCHEMBL5308927 | 0.85 | MEN1 (0.52) | MEN1KMT2ARXFP1TDP1NPC1 | |
| SCHEMBL5308372 | 0.83 | MEN1 (0.50) | MEN1KMT2ARXFP1TDP1NPC1 | |
| SCHEMBL5308968 | 0.83 | MEN1 (0.49) | MEN1KMT2ARXFP1NPC1PKM | |
| SCHEMBL15846311 | 0.82 | MEN1 (0.50) | HIF1AMEN1KMT2ARXFP1TDP1 | |
| SCHEMBL5308388 | 0.78 | THRA (0.48) | HIF1AMEN1KMT2ARXFP1NPC1 | |
| SCHEMBL5311312 | 0.78 | KMT2A (0.51) | MEN1KMT2ARXFP1NPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007038571-A2 | PROLYL HYDROXYLASE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-05 | — | — | WO | claimed |