SCHEMBL1584748

SCHEMBL1584748

Cc1ccccc1S(=O)O.[NaH]

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
ACHE P22303 2/20 0.41
G6PD P11413 1/20 0.39
KEAP1 Q14145 1/20 0.38
NFE2L2 Q16236 1/20 0.38
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
ALDH1A1 P00352 5/20 0.35
HPGD P15428 3/20 0.34
TDP1 Q9NUW8 3/20 0.34
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
KDM4E B2RXH2 1/20 0.33
GAA P10253 1/20 0.33
HSD17B10 Q99714 1/20 0.32
CYP3A4 P08684 1/20 0.32
MYC P01106 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29895885 0.98 TSHR (0.43) TSHRACHEG6PDKEAP1NFE2L2
SCHEMBL1652088 0.98 TSHR (0.43) TSHRACHEG6PDKEAP1NFE2L2
SCHEMBL4383783 0.95 TSHR (0.41) TSHRACHEG6PDKEAP1NFE2L2
SCHEMBL3152593 0.95 TSHR (0.41) TSHRACHEG6PDKEAP1NFE2L2
SCHEMBL28439337 0.95 TSHR (0.41) TSHRACHEG6PDKEAP1NFE2L2
Ammonia Solution, Strong SCHEMBL3156378 0.95 TSHR (0.41) TSHRACHEG6PDKEAP1NFE2L2
Ammonia Solution, Strong SCHEMBL3156386 0.95 TSHR (0.41) TSHRACHEG6PDKEAP1NFE2L2
SCHEMBL6421328 0.95 TSHR (0.41) TSHRACHEG6PDKEAP1NFE2L2
SCHEMBL3157627 0.95 TSHR (0.41) TSHRACHEG6PDKEAP1NFE2L2
SCHEMBL9652289 0.95 TSHR (0.41) TSHRACHEG6PDKEAP1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105153078-B A kind of thio oxa- cyclanes compound and its synthetic method 华南理工大学 2017-10-20 CN claimed
CN-105153078-A Thiooxacycloalkane compound and synthetic method therefor UNIV SOUTH CHINA TECH 2015-12-16 CN claimed
WO-2024190888-A1 DENTAL POLYMERIZATION KIT サンメディカル株式会社 2024-09-19 WO disclosed
WO-2024190887-A1 DENTAL POLYMERIZATION KIT サンメディカル株式会社 2024-09-19 WO disclosed
US-20240148613-A1 DENTAL POLYMERIZATION KIT SUN MEDICAL CO., LTD. (JP) 2024-05-09 US disclosed
WO-2024075641-A1 POLYMER MATERIAL FOR USE IN DENTISTRY サンメディカル株式会社 2024-04-11 WO disclosed
EP-4316453-A1 DENTAL POLYMERIZATION KIT Sun Medical Co., Ltd. (JP) 2024-02-07 EP disclosed
US-11844847-B2 Sulfur-containing polymerizable monomer and use thereof SUN MEDICAL CO., LTD. (JP) 2023-12-19 US disclosed
CN-113387855-B Method for synthesizing disulfide compound by visible light and titanocene complex concerted catalysis 陕西师范大学 2023-04-14 CN disclosed
CN-112940432-B Polymerizable monomer for dental material, composition, adhesive dental material, and kit 三井化学株式会社 2022-12-30 CN disclosed
WO-2022209944-A1 DENTAL POLYMERIZATION KIT サンメディカル株式会社 2022-10-06 WO disclosed
US-20020107422-A1 Process for producing allyl halide compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2002-08-08 US disclosed
US-6288138-B1 Dental adhesive kit SUN MEDICAL CO., LTD. (JP) 2001-09-11 US disclosed
US-6194410-B1 ANTISEROTONINE AGENTS; NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS HOFFMAN-LA ROCHE INC. 2001-02-27 US disclosed
EP-0941994-A1 Pyrazolopyrimidines and pyrazolotriazines with 5-HT6 receptor affinity F. HOFFMANN-LA ROCHE AG (CH) 1999-09-15 EP disclosed
EP-0923924-A2 Dental adhesive kit SUN MEDICAL CO., LTD. (JP) 1999-06-23 EP disclosed
EP-0579420-B1 Negative working resist material and pattern forming process WAKO PURE CHEM IND LTD (JP) 1997-03-05 EP disclosed
US-5389491-A Negative working resist composition MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1995-02-14 US disclosed
EP-0579420-A2 Negative working resist material and pattern forming process WAKO PURE CHEMICAL INDUSTRIES LTD (JP) 1994-01-19 EP disclosed
US-4211676-A Process for reclaiming scrap vulcanized rubber BRIDGESTONE TIRE COMPANY LIMITED (JP) 1980-07-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11844847-B2 Sulfur-containing polymerizable monomer and use thereof MGMT, SETDB1, ASH2L TSHR 4059/4885ACHE 4198/4885G6PD 2856/4885
US-20020107422-A1 Process for producing allyl halide compound ENY2, ZYX, RPS4Y1 TSHR 3103/4885ACHE 4330/4885G6PD 3142/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.