Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL3156378

Cc1ccccc1S(=O)O.N

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
ACHE P22303 2/20 0.41
G6PD P11413 1/20 0.39
KEAP1 Q14145 1/20 0.38
NFE2L2 Q16236 1/20 0.38
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
ALDH1A1 P00352 5/20 0.35
HPGD P15428 3/20 0.34
TDP1 Q9NUW8 3/20 0.34
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
KDM4E B2RXH2 1/20 0.33
GAA P10253 1/20 0.33
HSD17B10 Q99714 1/20 0.32
CYP3A4 P08684 1/20 0.32
MYC P01106 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL3156386 1.00 TSHR (0.41) TSHRACHEG6PDKEAP1NFE2L2
SCHEMBL29895885 0.98 TSHR (0.43) TSHRACHEG6PDKEAP1NFE2L2
SCHEMBL1652088 0.98 TSHR (0.43) TSHRACHEG6PDKEAP1NFE2L2
SCHEMBL9652289 0.95 TSHR (0.41) TSHRACHEG6PDKEAP1NFE2L2
SCHEMBL4383783 0.95 TSHR (0.41) TSHRACHEG6PDKEAP1NFE2L2
SCHEMBL28439337 0.95 TSHR (0.41) TSHRACHEG6PDKEAP1NFE2L2
SCHEMBL6421328 0.95 TSHR (0.41) TSHRACHEG6PDKEAP1NFE2L2
SCHEMBL1584748 0.95 TSHR (0.41) TSHRACHEG6PDKEAP1NFE2L2
SCHEMBL3157627 0.95 TSHR (0.41) TSHRACHEG6PDKEAP1NFE2L2
SCHEMBL3152593 0.95 TSHR (0.41) TSHRACHEG6PDKEAP1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240148613-A1 DENTAL POLYMERIZATION KIT SUN MEDICAL CO., LTD. (JP) 2024-05-09 US disclosed
EP-4316453-A1 DENTAL POLYMERIZATION KIT Sun Medical Co., Ltd. (JP) 2024-02-07 EP disclosed
US-11844847-B2 Sulfur-containing polymerizable monomer and use thereof SUN MEDICAL CO., LTD. (JP) 2023-12-19 US disclosed
CN-112940432-B Polymerizable monomer for dental material, composition, adhesive dental material, and kit 三井化学株式会社 2022-12-30 CN disclosed
WO-2022209944-A1 DENTAL POLYMERIZATION KIT サンメディカル株式会社 2022-10-06 WO disclosed
US-20210298997-A1 SULFUR-CONTAINING POLYMERIZABLE MONOMER AND USE THEREOF SUN MEDICAL CO., LTD. (JP) 2021-09-30 US disclosed
US-11110038-B2 Dental polymerizable monomers, compositions, adhesive dental materials and kits MITSUI CHEMICALS, INC. (JP) 2021-09-07 US disclosed
CN-107427414-B Polymerizable monomer for dental material, composition, adhesive dental material, and kit 三井化学株式会社 2021-07-02 CN disclosed
EP-3835289-A1 SULFUR-CONTAINING POLYMERIZABLE MONOMER AND USE THEREOF Sun Medical Co., Ltd. (JP) 2021-06-16 EP disclosed
CN-112940432-A Polymerizable monomer for dental material, composition, adhesive dental material, and kit 三井化学株式会社 2021-06-11 CN disclosed
US-8297975-B2 Reaction-curable adhesive composition and dental adhesive kit SUN MEDICAL CO., LTD. (JP) 2012-10-30 US disclosed
US-20100292359-A1 Reaction-Curable Adhesive Composition and Dental Adhesive Kit SUN MEDICAL CO., LTD. (JP) 2010-11-18 US disclosed
EP-1249221-B1 DENTAL ADHESIVE COMPOSITION TOKUYAMA DENTAL CORP (JP) 2010-10-13 EP disclosed
EP-2156817-A1 REACTION-SETTING ADHESIVE COMPOSITION, AND ADHESIVE MATERIAL KIT FOR DENTAL APPLICATIONS SUN MEDICAL CO., LTD. (JP) 2010-02-24 EP disclosed
EP-0923924-B1 Dental adhesive kit SUN MEDICAL CO LTD (JP) 2005-03-09 EP disclosed
US-6759449-B2 NONCROSSLINKING POLYMETHYL METHACRYLATE AND POLYETHYL METH-ACRYLATE SPHERICAL FILLER, UNSATURATED ACID FUNCTIONALIZED MONOMER AND POLYMERIZATION INITIATOR TOKUYAMA DENTAL CORPORATION (JP) 2004-07-06 US disclosed
US-20030050359-A1 Dental adhesive composition TOKUYAMA DENTAL CORPORATION (JP) 2003-03-13 US disclosed
EP-1249221-A1 DENTAL ADHESIVE COMPOSITION Tokuyama Dental Corporation (JP) 2002-10-16 EP disclosed
US-6288138-B1 Dental adhesive kit SUN MEDICAL CO., LTD. (JP) 2001-09-11 US disclosed
EP-0923924-A2 Dental adhesive kit SUN MEDICAL CO., LTD. (JP) 1999-06-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210298997-A1 SULFUR-CONTAINING POLYMERIZABLE MONOMER AND USE THEREOF MGMT, SETDB1, ASH2L TSHR 4059/4885ACHE 4198/4885G6PD 2856/4885
US-11844847-B2 Sulfur-containing polymerizable monomer and use thereof MGMT, SETDB1, ASH2L TSHR 4059/4885ACHE 4198/4885G6PD 2856/4885
US-20030050359-A1 Dental adhesive composition CAD, ASIC1, CD44 TSHR 4226/4885ACHE 4013/4885G6PD 1109/4885
US-11110038-B2 Dental polymerizable monomers, compositions, adhesive dental materials and kits ACTN1, SMCHD1, CAPZA1 TSHR 4160/4885ACHE 2879/4885G6PD 443/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.