Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR3 | P32745 | 13/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 13/20 | 0.50 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.44 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15848551 | 1.00 | SSTR3 (0.50) | SSTR3KCNH2SCN10ASSTR5MAPK13 | |
| SCHEMBL9280936 | 0.93 | MAPK13 (0.47) | SSTR3KCNH2SCN10AMAPK13MAPK12 | |
| SCHEMBL9284198 | 0.93 | MAPK13 (0.47) | SSTR3KCNH2SCN10AMAPK13MAPK12 | |
| SCHEMBL12160056 | 0.91 | MAPK13 (0.46) | SSTR3KCNH2SCN10AMAPK13MAPK12 | |
| SCHEMBL12160014 | 0.91 | MAPK13 (0.46) | SSTR3KCNH2SCN10AMAPK13MAPK12 | |
| SCHEMBL689813 | 0.91 | MAPK13 (0.46) | SSTR3KCNH2SCN10AMAPK13MAPK12 | |
| SCHEMBL18475635 | 0.91 | MAPK13 (0.46) | SSTR3KCNH2SCN10AMAPK13MAPK12 | |
| SCHEMBL12160094 | 0.91 | MAPK13 (0.46) | SSTR3KCNH2SCN10AMAPK13MAPK12 | |
| SCHEMBL2775603 | 0.91 | MAPK13 (0.46) | SSTR3KCNH2SCN10AMAPK13MAPK12 | |
| Hydrochloric Acid SCHEMBL19689541 | 0.90 | MAPK13 (0.45) | SSTR3KCNH2SCN10AMAPK13MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118852145-A | GSPT1 degradation agent and application thereof | 南京圣和药业股份有限公司 | 2024-10-29 | — | — | CN | disclosed |
| US-9868758-B2 | Betulinic proline imidazole derivatives as HIV inhibitors | HETERO LABS LIMITED (IN) | 2018-01-16 | — | — | US | disclosed |
| US-20170129916-A1 | NOVEL BETULINIC PROLINE IMIDAZOLE DERIVATIVES AS HIV INHIBITORS | HETERO RESEARCH FOUNDATION (IN) | 2017-05-11 | — | — | US | disclosed |
| US-20170129917-A1 | NOVEL BETULINIC PROLINE IMIDAZOLE DERIVATIVES AS HIV INHIBITORS | HETERO LABS LIMITED (IN) | 2017-05-11 | — | — | US | disclosed |
| US-20170129916-A1 | NOVEL BETULINIC PROLINE IMIDAZOLE DERIVATIVES AS HIV INHIBITORS | HETERO RESEARCH FOUNDATION (IN) | 2017-05-11 | — | — | US | disclosed |
| US-9637516-B2 | Betulinic acid proline derivatives as HIV inhibitors | HETERO RESEARCH FOUNDATION (IN) | 2017-05-02 | — | — | US | disclosed |
| US-20150337004-A1 | NOVEL BETULINIC ACID PROLINE DERIVATIVES AS HIV INHIBITORS | HETERO LABS LIMITED (IN) | 2015-11-26 | — | — | US | disclosed |
| WO-2014105926-A1 | NOVEL BETULINIC ACID PROLINE DERIVATIVES AS HIV INHIBITORS | HETERO RESEARCH FOUNDATION (IN) | 2014-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170129916-A1 | NOVEL BETULINIC PROLINE IMIDAZOLE DERIVATIVES AS HIV INHIBITORS | BET1, PRR12, PREP | SSTR3 4530/4885KCNH2 4692/4885SCN10A 4631/4885 |
| US-20170129917-A1 | NOVEL BETULINIC PROLINE IMIDAZOLE DERIVATIVES AS HIV INHIBITORS | BET1, PRR12, IMPA1 | SSTR3 4586/4885KCNH2 4678/4885SCN10A 4617/4885 |
| US-20150337004-A1 | NOVEL BETULINIC ACID PROLINE DERIVATIVES AS HIV INHIBITORS | BET1, PRR12, PELP1 | SSTR3 4779/4885KCNH2 4854/4885SCN10A 4509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.