SCHEMBL15848613

SCHEMBL15848613

CO[SiH](OC)c1ccccc1-c1cccc2cc3ccccc3cc12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.39
ALDH1A1 P00352 8/20 0.34
KDM4E B2RXH2 2/20 0.34
GAA P10253 2/20 0.34
HPGD P15428 4/20 0.33
HSD17B10 Q99714 4/20 0.33
HIF1A Q16665 3/20 0.33
TSHR P16473 2/20 0.33
MAPK1 P28482 2/20 0.33
CASP1 P29466 2/20 0.33
TP53 P04637 1/20 0.33
CASP7 P55210 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
CES1 P23141 1/20 0.33
CYP1A2 P05177 3/20 0.32
CYP2A6 P11509 1/20 0.32
MAPT P10636 3/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27886035 0.86 NQO1 (0.44) NQO1ALDH1A1KDM4EGAAHPGD
SCHEMBL15066697 0.84 MAPT (0.41) ALDH1A1KDM4EGAASMN1; SMN2CYP2A6
SCHEMBL15848274 0.83 HTR2A (0.33) NQO1ALDH1A1KDM4EGAAHPGD
SCHEMBL25393098 0.81 ALDH1A1 (0.42) NQO1ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL15848297 0.80 HPRT1 (0.47) ALDH1A1HPGDHSD17B10HIF1ATSHR
SCHEMBL15848276 0.78 ALDH1A1 (0.41) ALDH1A1KDM4EHPGDHSD17B10HIF1A
SCHEMBL29354014 0.78 ALDH1A1 (0.50) NQO1ALDH1A1KDM4EGAAHPGD
SCHEMBL2871930 0.78 ALDH1A1 (0.50) NQO1ALDH1A1KDM4EGAAHPGD
SCHEMBL15848461 0.77 ALDH1A1 (0.41) NQO1ALDH1A1KDM4EGAAHPGD
SCHEMBL15848066 0.77 ALDH1A1 (0.37) NQO1ALDH1A1KDM4EGAAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150344735-A1 Curable Silicone Composition, Cured Product Thereof, And Optical Semiconductor Device DOW CORNING TORAY CO., LTD. (JP) 2015-12-03 US disclosed
US-20150344636-A1 Curable Silicone Composition, Cured Product Thereof, And Optical Semiconductor Device DOW CORNING TORAY CO., LTD. (JP) 2015-12-03 US disclosed
WO-2014104388-A2 CURABLE SILICONE COMPOSITION, CURED PRODUCT THEREOF, AND OPTICAL SEMICONDUCTOR DEVICE DOW CORNING TORAY CO., LTD. (JP) 2014-07-03 WO disclosed
WO-2014104390-A2 CURABLE SILICONE COMPOSITION, CURED PRODUCT THEREOF, AND OPTICAL SEMICONDUCTOR DEVICE DOW CORNING TORAY CO., LTD. (JP) 2014-07-03 WO disclosed