Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 18/20 | 0.62 |
| ▸ | MMP2 | P08253 | 17/20 | 0.62 |
| ▸ | MMP3 | P08254 | 4/20 | 0.56 |
| ▸ | MMP13 | P45452 | 1/20 | 0.56 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.56 |
| ▸ | MMP1 | P03956 | 3/20 | 0.49 |
| ▸ | MMP8 | P22894 | 3/20 | 0.49 |
| ▸ | MMP14 | P50281 | 3/20 | 0.49 |
| ▸ | MMP25 | Q9NPA2 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15849271 | 1.00 | MMP9 (0.62) | MMP9MMP2MMP3MMP13ADAM17 | |
| SCHEMBL13272370 | 0.95 | MMP9 (0.71) | MMP9MMP2MMP3MMP13ADAM17 | |
| SCHEMBL15849270 | 0.95 | MMP9 (0.71) | MMP9MMP2MMP3MMP13ADAM17 | |
| SCHEMBL12244633 | 0.94 | MMP9 (0.60) | MMP9MMP2MMP3MMP13ADAM17 | |
| SCHEMBL12246386 | 0.94 | MMP9 (0.60) | MMP9MMP2MMP3MMP13ADAM17 | |
| SCHEMBL12244643 | 0.92 | MMP9 (0.58) | MMP9MMP2MMP3MMP13ADAM17 | |
| SCHEMBL12245543 | 0.92 | MMP9 (0.58) | MMP9MMP2MMP3MMP13ADAM17 | |
| SCHEMBL15849297 | 0.90 | MMP9 (0.56) | MMP9MMP2MMP3MMP13ADAM17 | |
| SCHEMBL15849302 | 0.90 | MMP9 (0.56) | MMP9MMP2MMP3MMP13ADAM17 | |
| SCHEMBL15849289 | 0.88 | MMP9 (0.57) | MMP9MMP2MMP3MMP13ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8765953-B2 | Compounds and methods for the treatment of pain and other diseases | AQUILUS PHARMACEUTICALS, INC. (US) | 2014-07-01 | — | — | US | disclosed |