Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.47 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12468464 | 0.89 | MEN1 (0.56) | MEN1KMT2ARAB9AALDH1A1NPC1 | |
| SCHEMBL12467647 | 0.88 | SCN9A (0.52) | MEN1KMT2ARAB9AALDH1A1NPC1 | |
| SCHEMBL15849567 | 0.84 | SCN9A (0.51) | MEN1KMT2ARAB9AALDH1A1NPC1 | |
| SCHEMBL12468471 | 0.79 | MEN1 (0.58) | MEN1KMT2ARAB9AALDH1A1NPC1 | |
| SCHEMBL12468521 | 0.79 | GRM1 (0.53) | MEN1KMT2ARAB9AALDH1A1NPC1 | |
| SCHEMBL15849569 | 0.78 | ALDH1A1 (0.58) | MEN1KMT2ARAB9AALDH1A1NPC1 | |
| SCHEMBL12468446 | 0.78 | ALDH1A1 (0.59) | MEN1KMT2ARAB9AALDH1A1NPC1 | |
| SCHEMBL13367649 | 0.76 | ALDH1A1 (0.74) | MEN1KMT2ARAB9AALDH1A1NPC1 | |
| SCHEMBL1802287 | 0.76 | ALDH1A1 (1.00) | MEN1KMT2ARAB9AALDH1A1NPC1 | |
| SCHEMBL12472603 | 0.75 | ESR2 (0.43) | MEN1KMT2ARAB9AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8765667-B2 | HCV protease inhibitors | EISSENSTAT MICHAEL (US) | 2014-07-01 | — | — | US | disclosed |