Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 3/20 | 0.66 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.66 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.66 |
| ▸ | POLA1 | P09884 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.41 |
| ▸ | ALB | P02768 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.41 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.41 |
| ▸ | ST6GAL1 | P15907 | 2/20 | 0.38 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.37 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2784191 | 1.00 | PDE3A (0.66) | PDE3APDE4DSLC29A1POLA1LMNA | |
| SCHEMBL2784189 | 1.00 | PDE3A (0.66) | PDE3APDE4DSLC29A1POLA1LMNA | |
| SCHEMBL13848155 | 1.00 | PDE3A (0.66) | PDE3APDE4DSLC29A1POLA1LMNA | |
| SCHEMBL10017432 | 1.00 | PDE3A (0.66) | PDE3APDE4DSLC29A1POLA1LMNA | |
| SCHEMBL10048580 | 1.00 | PDE3A (0.66) | PDE3APDE4DSLC29A1POLA1LMNA | |
| SCHEMBL2784182 | 1.00 | PDE3A (0.66) | PDE3APDE4DSLC29A1POLA1LMNA | |
| SCHEMBL23467204 | 0.91 | PDE4D (0.56) | PDE3APDE4DSLC29A1POLA1LMNA | |
| SCHEMBL10017438 | 0.91 | PDE3A (0.56) | PDE3APDE4DSLC29A1POLA1LMNA | |
| SCHEMBL6369145 | 0.91 | PDE4D (0.56) | PDE3APDE4DSLC29A1POLA1LMNA | |
| SCHEMBL23227420 | 0.91 | PDE4D (0.56) | PDE3APDE4DSLC29A1POLA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8765933-B2 | Asynthesis of β-nucleosides | PHARMAESSENTIA CORP. (TW) | 2014-07-01 | — | — | US | disclosed |