Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.56 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.56 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.56 |
| ▸ | POLA1 | P09884 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ST6GAL1 | P15907 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6369145 | 1.00 | PDE4D (0.56) | PDE4DPDE3ASLC29A1POLA1ALDH1A1 | |
| SCHEMBL27930788 | 1.00 | PDE4D (0.56) | PDE4DPDE3ASLC29A1POLA1ALDH1A1 | |
| SCHEMBL17841790 | 1.00 | PDE4D (0.56) | PDE4DPDE3ASLC29A1POLA1ALDH1A1 | |
| SCHEMBL23227420 | 1.00 | PDE4D (0.56) | PDE4DPDE3ASLC29A1POLA1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2689516 | 0.99 | PDE4D (0.55) | PDE4DPDE3ASLC29A1POLA1ALDH1A1 | |
| SCHEMBL10048580 | 0.91 | PDE3A (0.66) | PDE4DPDE3ASLC29A1POLA1POLB | |
| SCHEMBL2784191 | 0.91 | PDE3A (0.66) | PDE4DPDE3ASLC29A1POLA1POLB | |
| SCHEMBL15849797 | 0.91 | PDE3A (0.66) | PDE4DPDE3ASLC29A1POLA1POLB | |
| SCHEMBL2784182 | 0.91 | PDE3A (0.66) | PDE4DPDE3ASLC29A1POLA1POLB | |
| SCHEMBL10017432 | 0.91 | PDE3A (0.66) | PDE4DPDE3ASLC29A1POLA1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220411457-A1 | 2'-DEOXY-2',2'-DIFLUOROTETRAHYDROURIDINES WITH HIGH PURITY AND METHODS OF MAKING THE SAME | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2022-12-29 | — | — | US | disclosed |
| US-11028119-B2 | Synthetic route to 2′-deoxy-2′,2′-difluorotetrahydrouridines | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2021-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220411457-A1 | 2'-DEOXY-2',2'-DIFLUOROTETRAHYDROURIDINES WITH HIGH PURITY AND METHODS OF MAKING THE SAME | DCTD, DUT, DHODH | PDE4D 230/4885PDE3A 1942/4885SLC29A1 353/4885 |
| US-11028119-B2 | Synthetic route to 2′-deoxy-2′,2′-difluorotetrahydrouridines | DHFR, DPYD, DHODH | PDE4D 920/4885PDE3A 3383/4885SLC29A1 464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.