Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PLK4 | O00444 | 1/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | CHUK | O15111 | 1/20 | 0.48 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
| ▸ | PAK4 | O96013 | 1/20 | 0.48 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | PRKACA | P17612 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13941371 | 1.00 | RXFP1 (0.59) | RXFP1NPC1RAB9ATP53POLB | |
| SCHEMBL13941381 | 0.93 | EGFR (0.52) | RXFP1NPC1RAB9ATP53POLB | |
| SCHEMBL13941495 | 0.92 | EGFR (0.49) | RXFP1NPC1RAB9ATP53POLB | |
| SCHEMBL13941576 | 0.92 | NPC1 (0.61) | RXFP1NPC1RAB9ATP53POLB | |
| SCHEMBL16108828 | 0.91 | EGFR (0.56) | RXFP1NPC1RAB9ATP53POLB | |
| SCHEMBL13941390 | 0.91 | EGFR (0.50) | RXFP1NPC1RAB9ATP53POLB | |
| SCHEMBL13941451 | 0.91 | EGFR (0.56) | RXFP1NPC1RAB9ATP53POLB | |
| SCHEMBL13941389 | 0.90 | EGFR (0.49) | RXFP1NPC1RAB9ATP53POLB | |
| SCHEMBL13941375 | 0.90 | EGFR (0.49) | RXFP1NPC1RAB9ATP53POLB | |
| SCHEMBL13941448 | 0.89 | NHERF1 (0.63) | RXFP1NPC1RAB9AEGFRPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8765802-B2 | Kinase inhibitors, compositions thereof, and methods of use therewith | PROVID PHARMACEUTICALS, INC. (US) | 2014-07-01 | — | — | US | disclosed |