Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1A | P54750 | 15/20 | 0.59 |
| ▸ | PDE1B | Q01064 | 15/20 | 0.59 |
| ▸ | PDE1C | Q14123 | 15/20 | 0.59 |
| ▸ | PDE3B | Q13370 | 6/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 6/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL983806 | 0.88 | PDE1A (0.68) | PDE1APDE1BPDE1CPDE3BPDE3A | |
| SCHEMBL7746112 | 0.86 | PDE1A (0.65) | PDE1APDE1BPDE1CPDE3BPDE3A | |
| SCHEMBL16690970 | 0.81 | PDE1A (0.60) | PDE1APDE1BPDE1CPDE3BPDE3A | |
| SCHEMBL7746183 | 0.78 | PDE1A (0.61) | PDE1APDE1BPDE1CPDE3BPDE3A | |
| SCHEMBL13668874 | 0.77 | PDE1A (0.55) | PDE1APDE1BPDE1CPDE3BPDE3A | |
| SCHEMBL12350277 | 0.77 | PDE1A (0.56) | PDE1APDE1BPDE1CPDE3BPDE3A | |
| SCHEMBL7747219 | 0.76 | PDE1A (0.54) | PDE1APDE1BPDE1CPDE3BPDE3A | |
| SCHEMBL7746173 | 0.76 | PDE1A (0.55) | PDE1APDE1BPDE1CPDE3BPDE3A | |
| SCHEMBL7742053 | 0.75 | PDE1A (0.51) | PDE1APDE1BPDE1CPDE3BPDE3A | |
| SCHEMBL7749376 | 0.75 | PDE1A (0.51) | PDE1APDE1BPDE1CPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2749558-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE NAPHTHALENE COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2014-07-02 | — | — | EP | disclosed |