Tetrabuthylammonium

Tetrabuthylammonium

SCHEMBL158553

CCCC[N+](CCCC)(CCCC)CCCC.O=S(=O)([O-])OF

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SLC22A1 O15245 3/20 0.52
SLC22A2 O15244 1/20 0.46
RECQL P46063 2/20 0.45
TSHR P16473 2/20 0.45
GLA P06280 1/20 0.45
HPGD P15428 1/20 0.45
MAPK1 P28482 1/20 0.45
EPHX2 P34913 1/20 0.45
BLM P54132 1/20 0.45
ALDH1A1 P00352 1/20 0.42
TP53 P04637 1/20 0.42
CYP3A4 P08684 1/20 0.42
ALOX15 P16050 1/20 0.42
ALOX12 P18054 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HIF1A Q16665 1/20 0.42
HSD17B10 Q99714 1/20 0.42
DNM1 Q05193 4/20 0.39
FAAH O00519 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrabuthylammonium SCHEMBL10840728 0.84 SLC22A1 (0.55) SLC22A1SLC22A2RECQLTSHRGLA
Tetrabuthylammonium SCHEMBL1259012 0.84 SLC22A1 (0.55) SLC22A1SLC22A2RECQLTSHRGLA
Tetrabuthylammonium SCHEMBL991019 0.84 SLC22A1 (0.55) SLC22A1SLC22A2RECQLTSHRGLA
Tetrabuthylammonium SCHEMBL5574939 0.84 SLC22A1 (0.55) SLC22A1SLC22A2RECQLTSHRGLA
Tetrabuthylammonium SCHEMBL158552 0.84 SLC22A1 (0.60) SLC22A1SLC22A2TSHRALDH1A1TP53
Tetrabuthylammonium SCHEMBL27522614 0.84 SLC22A1 (0.60) SLC22A1SLC22A2TSHRALDH1A1TP53
Tetrabuthylammonium SCHEMBL243898 0.84 SLC22A1 (0.67) SLC22A1SLC22A2RECQLTSHRGLA
Tetrabuthylammonium SCHEMBL7757825 0.83 SLC22A1 (0.52) SLC22A1SLC22A2RECQLTSHRGLA
Tetrabuthylammonium SCHEMBL28818846 0.83 SLC22A1 (0.52) SLC22A1SLC22A2RECQLTSHRGLA
Tetrabuthylammonium SCHEMBL9795123 0.81 SLC22A1 (0.63) SLC22A1SLC22A2RECQLTSHRGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140228564-A1 PROCESSES OF ENANTIOSELECTIVELY FORMING AN AMINOXY COMPOUND AND AN 1,2-OXAZINE COMPOUND NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2014-08-14 US disclosed
US-20130341573-A1 PHOTOREFRACTIVE COMPOSITION COMPRISING ELECTROLYTES IN A PHOTOREFRACTIVE LAYER AND METHOD OF MAKING THEREOF NITTO DENKO CORPORATION (JP) 2013-12-26 US disclosed
EP-2612198-A1 SYSTEMS AND METHODS FOR IMPROVING THE PERFORMANCE OF A PHOTOREFRACTIVE DEVICE BY UTILIZING ELECTROLYTES Nitto Denko Corporation (JP) 2013-07-10 EP disclosed
US-20130163086-A1 SYSTEMS AND METHODS FOR IMPROVING THE PERFORMANCE OF A PHOTOREFRACTIVE DEVICE BY UTILIZING ELECTROLYTES NITTO DENKO CORPORATION (JP) 2013-06-27 US disclosed
WO-2012116071-A1 PHOTOREFRACTIVE COMPOSITION COMPRISING ELECTROLYTES IN A PHOTOREFRACTIVE LAYER AND METHOD OF MAKING THEREOF NITTO DENKO CORPORATION (JP) 2012-08-30 WO disclosed
WO-2012031025-A1 SYSTEMS AND METHODS FOR IMPROVING THE PERFORMANCE OF A PHOTOREFRACTIVE DEVICE BY UTILIZING ELECTROLYTES NITTO DENKO CORPORATION (JP) 2012-03-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140228564-A1 PROCESSES OF ENANTIOSELECTIVELY FORMING AN AMINOXY COMPOUND AND AN 1,2-OXAZINE COMPOUND AHR, CYP2S1, CYP1A1 SLC22A1 3282/4885SLC22A2 3095/4885RECQL 3131/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.