Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Tetrabuthylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 3/20 | 0.67 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | LSS | P48449 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrabuthylammonium SCHEMBL7634132 | 0.97 | SLC22A1 (0.63) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL28650062 | 0.97 | SLC22A1 (0.63) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL20550033 | 0.97 | SLC22A1 (0.63) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL28646343 | 0.97 | SLC22A1 (0.63) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL27541841 | 0.97 | SLC22A1 (0.63) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL28652897 | 0.97 | SLC22A1 (0.63) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL9795123 | 0.97 | SLC22A1 (0.63) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL24418 | 0.97 | SLC22A1 (0.63) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL5185312 | 0.97 | SLC22A1 (0.63) | SLC22A1SLC22A2TSHRALDH1A1TP53 | |
| Tetrabuthylammonium SCHEMBL317533 | 0.95 | SLC22A1 (0.60) | SLC22A1SLC22A2TSHRALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2508 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122079810-A | Aromatic diamine and polyimide containing amido, preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| EP-4705547-A1 | PROCESS FOR THE PREPARATION OF 1,1,4,4-TETRAALKYLOXY-2-BUTENE | DSM IP Assets B.V. (NL) | 2026-03-11 | — | — | EP | claimed |
| CN-116726545-B | Magnetic solid phase extraction method and application thereof | 中国水产科学研究院南海水产研究所 | 2026-02-27 | — | — | CN | claimed |
| US-20260015560-A1 | COMPOSITIONS FOR POST-CMP CLEANING OF MICROELECTRONIC DEVICES | ENTEGRIS INC (US) | 2026-01-15 | — | — | US | claimed |
| US-20250353823-A1 | PROCESS FOR THE PREPARATION OF ALKOXYLATED 2,5-DIHYDROFURAN | DSM IP ASSETS BV (NL) | 2025-11-20 | — | — | US | claimed |
| CN-120040411-A | Method for preparing aryl crown ether compound by one-pot method | 浙江大学衢州研究院 | 2025-05-27 | — | — | CN | claimed |
| WO-2025106486-A1 | AQUEOUS ZN-TETRAZINE BATTERIES | OHIO STATE INNOVATION FOUNDATION (US) | 2025-05-22 | — | — | WO | claimed |
| EP-4540440-A1 | PROCESS FOR THE PREPARATION OF ALKOXYLATED 2,5-DIHYDROFURAN | DSM IP Assets B.V. (NL) | 2025-04-23 | — | — | EP | claimed |
| CN-119161652-B | Composite drainage net material and preparation method thereof | 山东亿博阳光工程材料有限公司 | 2025-03-25 | — | — | CN | claimed |
| CN-119663302-A | Method for preparing organic phosphine oxide by electrolytic oxidation | 中国石油化工股份有限公司 | 2025-03-21 | — | — | CN | claimed |
| EP-0092998-B1 | ETHERIFICATION PROCESS FOR HEXITOLS AND ANHYDROHEXITOLS | ICI AMERICAS INC. (US) | 1986-03-12 | — | — | EP | claimed |
| EP-0079623-B1 | PROCESS FOR THE PREPARATION OF 1H-PYRROLE-2-ACETIC ESTERS | RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) | 1985-08-21 | — | — | EP | claimed |
| US-4522729-A | CXONTACTING IMPORITIES WITH TETRAALKYLAMMONIUM SALT | PHILLIPS PETROLEUM COMPANY (US) | 1985-06-11 | — | — | US | claimed |
| US-4493935-A | SAPONIFICATION IH-PYRROL-2-ACETONITRILE (OR-ACETAMIDE), THEN 7AR-) | RUTGERSWERKE AKTIENGESELLSCHAFT (DE) | 1985-01-15 | — | — | US | claimed |
| US-4435586-A | POLYALKYLATION OF SORBITOL, SORBITAN, AND ISISORBIDE | ICI AMERICAS INC., A CORP. OF DE | 1984-03-06 | — | — | US | claimed |
| EP-0092998-A1 | Etherification process for hexitols and anhydrohexitols | ICI AMERICAS INC. (US) | 1983-11-02 | — | — | EP | claimed |
| EP-0005001-B1 | POLYMERISATION OF 2-PYRROLIDONE WITH ALKALI METAL PYRROLIDONATES AND QUATERNARY AMMONIUM SALTS, AND POLYMERISATION PRODUCTS THUS OBTAINED | Barnes, Arthur Conard (US) | 1982-06-02 | — | — | EP | claimed |
| US-4217442-A | Polymerization of 2-pyrrolidone with alkali metal pyrrolidonates and certain quaternary ammonium salts | BARNES ARTHUR C (US) | 1980-08-12 | — | — | US | claimed |
| WO-1979000971-A1 | POLYMERIZATION OF 2-PYRROLIDONE | BARNES C (US) | 1979-11-29 | — | — | WO | claimed |
| EP-0005001-A1 | Polymerisation of 2-pyrrolidone with alkali metal pyrrolidonates and quaternary ammonium salts, and polymerisation products thus obtained | Barnes, Arthur Conard (US) | 1979-10-31 | — | — | EP | claimed |