Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 2/20 | 0.41 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 4/20 | 0.37 |
| ▸ | MAOB | P27338 | 4/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15945689 | 0.96 | KDM4E (0.43) | CDK4CDK6DYRK1AKDM4EATM | |
| SCHEMBL15945610 | 0.96 | CDK4 (0.43) | CDK4CDK6DYRK1AKDM4EATM | |
| SCHEMBL15855398 | 0.96 | KDM4E (0.43) | CDK4CDK6DYRK1AKDM4EATM | |
| SCHEMBL15945627 | 0.95 | CDK4 (0.40) | CDK4CDK6DYRK1AKDM4EATM | |
| SCHEMBL15945625 | 0.95 | CDK4 (0.43) | CDK4CDK6DYRK1AKDM4EATM | |
| SCHEMBL15945682 | 0.93 | L3MBTL1 (0.49) | CDK4CDK6DYRK1AKDM4EATM | |
| SCHEMBL25946458 | 0.92 | KDM4E (0.44) | CDK4CDK6DYRK1AKDM4EATM | |
| SCHEMBL12114929 | 0.92 | KDM4E (0.44) | CDK4CDK6DYRK1AKDM4EATM | |
| SCHEMBL15945609 | 0.92 | KDM4E (0.47) | CDK4CDK6DYRK1AKDM4EATM | |
| SCHEMBL15945750 | 0.91 | ATM (0.41) | CDK4CDK6DYRK1AKDM4EATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9537111-B2 | Compound, material for organic electroluminescence device, and organic electroluminescence device | IDEMITSU KOSAN CO., LTD. (JP) | 2017-01-03 | — | — | US | disclosed |
| US-20140183486-A1 | NOVEL COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, AND ORGANIC ELECTROLUMINESCENCE DEVICE | IDEMITSU KOSAN CO., LTD (JP) | 2014-07-03 | — | — | US | disclosed |
| US-20140183486-A1 | NOVEL COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, AND ORGANIC ELECTROLUMINESCENCE DEVICE | IDEMITSU KOSAN CO., LTD (JP) | 2014-07-03 | — | — | US | disclosed |