SCHEMBL15855428

SCHEMBL15855428

c1cc(-c2cccc(-c3cccc4c3oc3ccccc34)c2)cc(-c2ccc3oc4ccc(-c5cccc(-c6cccc7c6oc6ccccc67)c5)cc4c3c2)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.64
GGPS1 O95749 1/20 0.50
PLA2G2A P14555 4/20 0.47
PLA2G4A P47712 4/20 0.47
PLA2G10 O15496 1/20 0.47
PRKDC P78527 5/20 0.46
PTGES2 Q9H7Z7 1/20 0.46
NPC1 O15118 2/20 0.45
MAPT P10636 2/20 0.45
KDM4E B2RXH2 1/20 0.45
MEN1 O00255 1/20 0.45
ALDH1A1 P00352 1/20 0.45
HPGD P15428 1/20 0.45
RAB9A P51151 1/20 0.45
KMT2A Q03164 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
HSP90AA1 P07900 1/20 0.42
HSP90AB1 P08238 1/20 0.42
AHR P35869 2/20 0.41
PRMT5 O14744 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14410427 1.00 ALOX5 (0.64) ALOX5GGPS1PLA2G2APLA2G4APLA2G10
SCHEMBL15855426 1.00 ALOX5 (0.64) ALOX5GGPS1PLA2G2APLA2G4APLA2G10
SCHEMBL20277164 0.97 ALOX5 (0.61) ALOX5GGPS1PLA2G2APLA2G4APLA2G10
SCHEMBL15855433 0.97 ALOX5 (0.60) ALOX5GGPS1PLA2G2APLA2G4APLA2G10
SCHEMBL20276902 0.95 ALOX5 (0.62) ALOX5GGPS1PLA2G2APLA2G4APLA2G10
SCHEMBL20277273 0.95 ALOX5 (0.62) ALOX5GGPS1PLA2G2APLA2G4APLA2G10
SCHEMBL12069400 0.95 ALOX5 (0.69) ALOX5GGPS1PLA2G2APLA2G4APLA2G10
SCHEMBL20277131 0.95 ALOX5 (0.69) ALOX5GGPS1PLA2G2APLA2G4APLA2G10
SCHEMBL126822 0.94 ALOX5 (0.58) ALOX5GGPS1PLA2G2APLA2G4APLA2G10
SCHEMBL17057220 0.94 ALOX5 (0.57) ALOX5GGPS1PLA2G2APLA2G4APLA2G10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9537111-B2 Compound, material for organic electroluminescence device, and organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2017-01-03 US disclosed
US-20140183486-A1 NOVEL COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD (JP) 2014-07-03 US disclosed
US-20140183486-A1 NOVEL COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD (JP) 2014-07-03 US disclosed