SCHEMBL15856425

SCHEMBL15856425

CN(c1ccccc1F)c1c(-c2cccc(-c3ccccc3)c2)ccc(-c2ccccc2)c1F

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A9 P48067 1/20 0.33
ACLY P53396 2/20 0.33
TACR1 P25103 1/20 0.32
PTGER1 P34995 1/20 0.32
PTGER4 P35408 1/20 0.32
PTGER3 P43115 1/20 0.32
PTGER2 P43116 1/20 0.32
OPRD1 P41143 1/20 0.32
PTGS1 P23219 3/20 0.31
MEN1 O00255 2/20 0.31
PTGS2 P35354 2/20 0.31
KMT2A Q03164 2/20 0.31
FABP2 P12104 1/20 0.31
TSHR P16473 1/20 0.31
AKR1C4 P17516 1/20 0.31
ADRA2B P18089 1/20 0.31
CHRM3 P20309 1/20 0.31
HTR2C P28335 1/20 0.31
DRD3 P35462 1/20 0.31
AKR1C3 P42330 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15856325 1.00 SLC6A9 (0.33) SLC6A9ACLYTACR1PTGER1PTGER4
SCHEMBL15856506 0.91 SLC6A9 (0.33) SLC6A9TACR1
SCHEMBL15856397 0.91 SLC6A9 (0.33) SLC6A9TACR1
SCHEMBL15856443 0.91 TACR1 (0.33) TACR1PTGS1MEN1PTGS2KMT2A
SCHEMBL15856408 0.90 AKR1C3 (0.39) OPRD1AKR1C3AKR1C2
SCHEMBL15856495 0.90 AKR1C3 (0.39) OPRD1AKR1C3AKR1C2
SCHEMBL15856338 0.87 AKR1C3 (0.36) SLC6A9ACLYMEN1KMT2AAKR1C3
SCHEMBL15856442 0.87 AKR1C3 (0.36) SLC6A9ACLYMEN1KMT2AAKR1C3
SCHEMBL15856509 0.87 SLC6A9 (0.35) SLC6A9ACLYTACR1PTGER1PTGER4
SCHEMBL15856349 0.87 AKR1C3 (0.38) SLC6A9PTGS2AKR1C3AKR1C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140183468-A1 PYRENE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DIODE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-07-03 US disclosed