SCHEMBL15856432

SCHEMBL15856432

CN(c1ccccc1F)c1cc(-c2cccc3ccccc23)ccc1F

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.40
ACMSD Q8TDX5 1/20 0.40
PPARG P37231 5/20 0.37
PPARA Q07869 5/20 0.37
SIGMAR1 Q99720 1/20 0.37
ENPP3 O14638 1/20 0.37
ENPP1 P22413 1/20 0.37
CA12 O43570 2/20 0.36
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA9 Q16790 2/20 0.36
AKR1C3 P42330 1/20 0.36
AKR1C2 P52895 1/20 0.36
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
MAPK11 Q15759 1/20 0.35
MAPK14 Q16539 1/20 0.35
CYP11B1 P15538 2/20 0.35
CYP11B2 P19099 2/20 0.35
CYP2C9 P11712 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15856551 0.91 MCL1 (0.40) MCL1ACMSDPPARGPPARASIGMAR1
SCHEMBL15856492 0.87 PPARG (0.40) MCL1ACMSDPPARGPPARASIGMAR1
SCHEMBL15856332 0.87 PPARG (0.40) MCL1ACMSDPPARGPPARASIGMAR1
SCHEMBL15856406 0.85 PPARG (0.36) MCL1ACMSDPPARGPPARASIGMAR1
SCHEMBL15856328 0.85 PPARG (0.36) MCL1ACMSDPPARGPPARASIGMAR1
SCHEMBL15856339 0.83 CA12 (0.39) MCL1ACMSDPPARGPPARAENPP3
SCHEMBL15856327 0.83 SLC6A9 (0.35) MCL1ACMSDPPARGPPARASIGMAR1
SCHEMBL15856457 0.83 CA12 (0.39) MCL1ACMSDPPARGPPARAENPP3
SCHEMBL15856419 0.82 CA12 (0.36) MCL1ACMSDPPARGPPARASIGMAR1
SCHEMBL15852986 0.82 PPARG (0.38) MCL1ACMSDPPARGPPARASIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140183468-A1 PYRENE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DIODE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-07-03 US disclosed