Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.36 |
| ▸ | PPARA | Q07869 | 8/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15856464 | 1.00 | PPARG (0.36) | PPARGPPARACYP2C9CYP2C19PPARD | |
| SCHEMBL15856338 | 0.95 | AKR1C3 (0.36) | PPARGPPARACYP2C9CYP2C19PPARD | |
| SCHEMBL15856442 | 0.95 | AKR1C3 (0.36) | PPARGPPARACYP2C9CYP2C19PPARD | |
| SCHEMBL15856397 | 0.87 | SLC6A9 (0.33) | RXRARXRBSLC6A9 | |
| SCHEMBL15856506 | 0.87 | SLC6A9 (0.33) | RXRARXRBSLC6A9 | |
| SCHEMBL15856443 | 0.87 | TACR1 (0.33) | CYP2C9CYP2C19AKR1C3AKR1C2RXRA | |
| SCHEMBL15856342 | 0.85 | PPARG (0.36) | PPARGPPARACYP2C9CYP2C19PPARD | |
| SCHEMBL15856340 | 0.85 | PPARG (0.36) | PPARGPPARACYP2C9CYP2C19PPARD | |
| SCHEMBL15853064 | 0.84 | PPARG (0.39) | PPARGPPARACYP2C9CYP2C19PPARD | |
| SCHEMBL15853057 | 0.84 | PPARG (0.39) | PPARGPPARACYP2C9CYP2C19PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140183468-A1 | PYRENE-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DIODE COMPRISING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2014-07-03 | — | — | US | disclosed |