Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 16/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.41 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1586070 | 0.86 | HIF1A (0.49) | HIF1AEGLN1EGLN3 | |
| SCHEMBL1585967 | 0.84 | EGLN1 (0.45) | HIF1AEGLN1 | |
| SCHEMBL1586566 | 0.82 | EGLN1 (0.46) | HIF1AEGLN1 | |
| SCHEMBL1586442 | 0.81 | HIF1A (0.48) | HIF1AEGLN1EGLN3 | |
| SCHEMBL1585831 | 0.81 | HIF1A (0.48) | HIF1AEGLN1EGLN3 | |
| SCHEMBL1585620 | 0.80 | EGLN1 (0.48) | HIF1AEGLN1EGLN3 | |
| SCHEMBL1586142 | 0.79 | EGLN1 (0.43) | HIF1AEGLN1 | |
| SCHEMBL1585782 | 0.79 | EGLN1 (0.43) | HIF1AEGLN1 | |
| SCHEMBL1586046 | 0.79 | EGLN1 (0.43) | HIF1AEGLN1 | |
| SCHEMBL1586480 | 0.78 | EGLN1 (0.47) | HIF1AEGLN1EGLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011048611-A1 | NOVEL FUSED PYRIDAZINE DERIVATIVES | TORRENT PHARMACEUTICALS LIMITED (IN) | 2011-04-28 | — | — | WO | claimed |
| WO-2011048611-A1 | NOVEL FUSED PYRIDAZINE DERIVATIVES | TORRENT PHARMACEUTICALS LIMITED (IN) | 2011-04-28 | — | — | WO | disclosed |