SCHEMBL1586046

SCHEMBL1586046

CN(C)c1ccc2nc3c(O)c(C(=O)NCC(=O)O)c(=O)n(C)n3c2c1

nearest known ligand 0.43

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 3/20 0.43
HIF1A Q16665 17/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1586070 0.87 HIF1A (0.49) EGLN1HIF1A
SCHEMBL1585967 0.87 EGLN1 (0.45) EGLN1HIF1A
SCHEMBL1586442 0.86 HIF1A (0.48) EGLN1HIF1A
SCHEMBL1586142 0.84 EGLN1 (0.43) EGLN1HIF1A
SCHEMBL1585684 0.84 EGLN3 (0.44) EGLN1HIF1A
SCHEMBL1586480 0.83 EGLN1 (0.47) EGLN1HIF1A
SCHEMBL1585620 0.83 EGLN1 (0.48) EGLN1HIF1A
SCHEMBL1586566 0.82 EGLN1 (0.46) EGLN1HIF1A
SCHEMBL1585831 0.80 HIF1A (0.48) EGLN1HIF1A
SCHEMBL1585664 0.79 HIF1A (0.43) EGLN1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011048611-A1 NOVEL FUSED PYRIDAZINE DERIVATIVES TORRENT PHARMACEUTICALS LIMITED (IN) 2011-04-28 WO claimed